RecruitingNot ApplicableNCT05906810

Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis

Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis: a Randomized-controlled Clinical Trial.


Sponsor

University of Catania

Enrollment

90 participants

Start Date

Oct 5, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment on endothelial dysfunction parameters in subjects with peri-implantitis/peri-implant mucositis and without any cardiovascular disease.


Eligibility

Inclusion Criteria4

  • PERI-IMPLANTITIS GROUP
  • Clinically diagnosed with peri-implantitis according to the EFP/AAP 2017 criteria.
  • Clinically diagnosed with peri-implant mucositis according to the EFP/AAP 2017 criteria.
  • Clinically diagnosed with healthy periodontum withouth periodontitis history according to the EFP/AAP 2017 criteria.

Exclusion Criteria11

  • Periodontal treatment, implant surgery, antibiotics, NSAIDs, immunosuppressants during the last 6 months.
  • Pregnancy.
  • Cardiovascular Diseases.
  • PERI-IMPLANT MUCOSITIS GROUP
  • Periodontal treatment, implant surgery, antibiotics, NSAIDs, immunosuppressants during the last 6 months.
  • Pregnancy.
  • Cardiovascular Diseases.
  • HEALTHY GROUP
  • Scaling, antibiotics, NSAIDs, immunosuppressants during the last 6 months.
  • Pregnancy.
  • Cardiovascular Diseases.

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Interventions

PROCEDURENon-surgical periodontal treatment

Subgingival biofilm ultrasonic debridement


Locations(1)

AOU Policlinico G. Rodolico

Catania, Italy

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NCT05906810


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