RecruitingNot ApplicableNCT05936697

Neurofeedback Training For Older Adults

Neurofeedback Training to Improve Prefrontal Functioning in Older Adults With Subclinical Depression and Anxiety: a Randomised Control Trial


Sponsor

The Hong Kong Polytechnic University

Enrollment

90 participants

Start Date

Feb 15, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Symptoms of depression and anxiety are common in older adults and are associated with poor outcomes and the risk of dementia. The prefrontal cortex (PFC) is crucial for emotion regulation. Poor PFC function may underlie subclinical depression and anxiety symptoms in older people, which could progress to clinical conditions. Neurofeedback training based on electroencephalography (EEG) or functional near-infrared spectroscopy (fNIRS) teaches individuals to self-regulate different aspects of brain activity and induce neurocognitive improvements. This proposed project will examine whether prefrontal EEG and fNIRS neurofeedback training programmes can enhance the mood and cognition of older adults with subclinical depression and anxiety.


Eligibility

Min Age: 60 YearsMax Age: 79 Years

Plain Language Summary

Simplified for easier understanding

This study is testing neurofeedback brain training — a technique where people learn to regulate their own brain activity using real-time feedback — to help older adults reduce feelings of anxiety and depression. Sessions are conducted in Hong Kong and are in Chinese. **You may be eligible if...** - You are aged 60–79 - You are right-handed - You have moderate or higher levels of depression or anxiety (based on a standardized questionnaire) - You have no history of neurological or psychiatric disorders - You have not had a traumatic brain injury requiring hospitalization - You are not currently taking psychiatric medications - You can read Traditional Chinese and have normal or corrected-to-normal vision - You scored at least 19 on a cognitive screening test **You may NOT be eligible if...** - You have a history of brain injury, neurological disease, or psychiatric conditions - You are currently on psychotropic (psychiatric) medications - You do not meet the age, handedness, or cognitive screening requirements Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEfNIRS

For fNIRS to be recorded by the wearable OctaMon+ system (Artinis Medical Systems, The Netherlands), two sources, each surrounded by four detectors positioned approximately 3 cm apart, will be placed on the scalp such that the two channels near the fissure on each side of the head are surrounded F3 and F4. Data will be sampled at 50 Hz.

DEVICEEEG

For EEG to be recorded by the ANT eego rt8 amplifier (ANT Neuro, Hengelo, The Netherlands), electrodes will be placed at Fp1, F3, F4, Fz, Fpz, Cz, GND (ground), lower VEOG, and on the two earlobes (references). Data will be collected at 2,048 Hz.

OTHERBaseline Training

In the sham condition, participants will receive visual feedback based on pre-recordings and/or other participants' recordings. Participants will undergo a 3-min rest period before and after each training session to track changes in resting-state brain activity within and across sessions.


Locations(1)

Faculty of Health and Social Sciences OF The Hong Kong Polytechnic University

Hong Kong, Hong Kong

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NCT05936697


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