RecruitingNot ApplicableNCT06180837

Effect of Sleep Extension on Ceramides in People with Overweight and Obesity

Biomarkers of Habitual Short Sleep and Related Cardiometabolic Risk


Sponsor

University of Utah

Enrollment

70 participants

Start Date

Feb 12, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity. Participants will undergo a randomized controlled trial, with sleep extension (intervention) and healthy lifestyle (control) groups. The sleep extension is designed to increase participant's time in bed by 2 hours per night. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, and nutrition when eating out).


Eligibility

Min Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This study looks at whether extending sleep duration — getting more sleep each night — reduces levels of ceramides in the blood. Ceramides are fats linked to heart disease risk, and people who sleep less than 6.5 hours per night tend to have higher levels. The study tests whether simply sleeping more can lower this risk. **You may be eligible if...** - You are between 18 and 45 years old - Your BMI is between 27.5 and 34.9 (overweight or mildly obese range) - You regularly sleep fewer than 6.5 hours per night on average - You do not have a diagnosed sleep disorder **You may NOT be eligible if...** - You have a diagnosed sleep condition (like sleep apnea or insomnia) - You have major health conditions that affect sleep or metabolism - You are pregnant or breastfeeding - You work night shifts or have irregular sleep schedules that cannot be changed Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALSleep Extension Intervention

Sleep extension-based intervention focused on increasing time spent in bed by 2 hours per night by directly scheduling assigned bed and waketimes based on participant's individual schedules. Participants will receive weekly sleep tips and counseling on improving their sleep duration.


Locations(1)

College of Health Research Complex--University of Utah

Salt Lake City, Utah, United States

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NCT06180837


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