Insulin Sensitivity Clinical Trials

26 recruiting

Insulin Sensitivity Trials at a Glance

32 actively recruiting trials for insulin sensitivity are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 22 trials, with the heaviest enrollment activity in Aurora, Salt Lake City, and Baton Rouge. Lead sponsors running insulin sensitivity studies include University of Colorado, Denver, University of Copenhagen, and University of Utah.

Browse insulin sensitivity trials by phase

Treatments under study

About Insulin Sensitivity Clinical Trials

Looking for clinical trials for Insulin Sensitivity? There are currently 26 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Insulin Sensitivity trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Insulin Sensitivity clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 32 trials

Recruiting
Not Applicable

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling

ObesityInsulin ResistanceMuscle Weakness+2 more
University of Colorado, Denver70 enrolled1 locationNCT06129110
Recruiting
Not Applicable

Metabolic Adaptations to Weight Loss With and Without Exercise

ObesityInsulin ResistanceWeight Loss+3 more
University of Michigan68 enrolled1 locationNCT05806801
Recruiting
Not Applicable

High Intensity Interval Training and Insulin Sensitivity in Type 2 Diabetes

Insulin Sensitivity/ResistanceType 2 DiabetesLifestyle-related Condition
Finis Terrae University36 enrolled1 locationNCT06688461
Recruiting
Not Applicable

Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids

Insulin Sensitivity/ResistanceInflammationType 2 Diabetes+1 more
Institut de Recherches Cliniques de Montreal48 enrolled1 locationNCT04485871
Recruiting
Phase 1

A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes Mellitus

Diabetes MellitusInsulin Sensitivity
Eli Lilly and Company95 enrolled1 locationNCT06982859
Recruiting
Phase 2

The Effect of Colchicine, on Insulin Sensitivity in Individuals With Type 1 Diabetes and Systemic Low-grade Inflammation

Type 1 DiabetesInsulin SensitivityChronic Inflammation
Asger Lund, MD26 enrolled1 locationNCT07247734
Recruiting
Not Applicable

The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)

Blood PressureWeight GainInsulin Sensitivity+2 more
Arkansas Children's Hospital Research Institute150 enrolled2 locationsNCT05992688
Recruiting
Not Applicable

Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers

Metabolic DiseaseBlood PressureInsulin Sensitivity+1 more
Colorado State University50 enrolled1 locationNCT06550115
Recruiting
Not Applicable

Non-Nutritive Sweetener Consumption and Glucose Homeostasis in Older Adults With Prediabetes

Continuous Glucose MonitoringInsulin SensitivityInflammatory Markers+1 more
Virginia Polytechnic Institute and State University30 enrolled1 locationNCT05337098
Recruiting
Not Applicable

Effect of Physiologic Insulin Administration on Insulin Sensitivity and Cognition

Insulin SensitivityAlzheimer s DiseaseAlzheimer Blood Biomarkers
Pennington Biomedical Research Center8 enrolled1 locationNCT07265323
Recruiting
Not Applicable

Physical Activity and Insulin Sensitivity Dynamics

Insulin Sensitivity
University of Copenhagen8 enrolled1 locationNCT06776094
Recruiting
Not Applicable

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

Insulin Sensitivity/ResistanceObesityInsulin Resistance+14 more
Pichamol Jirapinyo, MD, MPH132 enrolled2 locationsNCT06138821
Recruiting
Not Applicable

Countermeasures to Circadian Misalignment

Metabolic DiseaseInsulin SensitivityCircadian Rhythm Sleep Disorder of Shift Work Type
Colorado State University32 enrolled1 locationNCT04966351
Recruiting
Phase 2

NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals

Diabetes MellitusInsulin Sensitivity/ResistanceCardiovascular Diseases+4 more
University of Alabama at Birmingham200 enrolled1 locationNCT04055428
Recruiting
Phase 1

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

Cardiovascular DiseasesEndothelial DysfunctionType 1 Diabetes+2 more
Kalie Tommerdahl60 enrolled2 locationsNCT05065372
Recruiting

Puberty Suppression and Cardiometabolic Health

Insulin Sensitivity/ResistanceEndothelial DysfunctionVascular Stiffness+1 more
University of Colorado, Denver30 enrolled1 locationNCT04482374
Recruiting

Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth

Gender DysphoriaInsulin SensitivityTransgenderism
University of Colorado, Denver90 enrolled1 locationNCT04596592
Recruiting
Not Applicable

Evaluation of Molecular Hydrogen Supplementation to Enhance the Efficacy of Weight Loss Retreat in Overweight and Obese Adolescents

Body CompositionInflammationOxidative Stress+4 more
Palacky University60 enrolled1 locationNCT06961110
Recruiting
Not Applicable

Mechanisms of Ultrasound Neuromodulation Effects in Diabetes

Insulin Sensitivity
Yale University77 enrolled1 locationNCT06042517
Recruiting
Phase 4

Evaluating the Efficacy of Topical Insulin for the Restoration of Ocular Surface Interface in Dry Eye Disease.

Dry EyeInsulin Sensitivity
Khyber Teaching Hospital126 enrolled1 locationNCT06939959