RecruitingNCT06211868

Redirecting Immune, Lipid and Metabolic Drivers of Early Cardiovascular Disease: The RESET Cohort Study


Sponsor

National University Hospital, Singapore

Enrollment

3,000 participants

Start Date

Mar 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Project RESET is a Singapore National Medical Research Council Large Collaborative Grant funded program that brings together a nationwide community of cardiovascular, metabolic, and digital health researchers, as well as clinicians across primary and tertiary care to study the immune, lipid and metabolic drivers of early cardiovascular disease. RESET incorporates a nested randomised controlled trials (RCT) to test the use of a combined digital wearable and AI-human symbiotic lifestyle intervention to halt or reverse the progression of early disease.


Eligibility

Min Age: 40 YearsMax Age: 70 Years

Inclusion Criteria2

  • -70 years old
  • ASCVD (atherosclerotic cardiovascular disease) score of 5% and higher

Exclusion Criteria4

  • Previous major cardiovascular disease (myocardial infarction, heart failure, ischemic stroke)
  • Limited life expectancy
  • Other ongoing unstable medical conditions
  • Pregnant women

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Interventions

BEHAVIORALDigital wearable and AI-human symbiotic lifestyle intervention

Digital wearable and AI-human symbiotic lifestyle intervention


Locations(1)

NUS

Singapore, Singapore

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NCT06211868


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