RecruitingNCT06228677

Comparison of Catecholamine Concentrations in Venous Blood During Selective Adrenal Artery Embolization

Comparison of Catecholamine Concentrations in Adrenal Venous Blood and Peripheral Venous Blood During Percutaneous Selective Adrenal Artery Embolization in Hypertensive Patients With Primary Aldosteronism: A Prospective Cohort Study


Sponsor

First Affiliated Hospital of Chengdu Medical College

Enrollment

196 participants

Start Date

Sep 18, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

To explore the relationship between perioperative blood pressure and catecholamine concentrations in adrenal venous blood and peripheral venous blood in hypertensive patients with primary aldosteronism (PA) who underwent percutaneous selective adrenal artery embolization (SAAE). In order to elucidate the related phenomena and possible mechanisms of blood pressure fluctuations caused by SAAE treatment in hypertensive patients with PA.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is measuring hormone levels (specifically catecholamines) in blood taken from the adrenal vein during a minimally invasive procedure called selective adrenal artery embolization. It is aimed at improving how doctors treat primary aldosteronism — a condition where the adrenal glands produce too much of a hormone that raises blood pressure. **You may be eligible if...** - You are 18 or older with a confirmed diagnosis of primary aldosteronism (a hormonal cause of high blood pressure) - Your blood pressure remains high (140/90 mmHg or above in clinic, or above certain thresholds on 24-hour monitoring) - Your adrenal CT scan shows changes consistent with aldosteronism - You have had high blood pressure for more than 6 months **You may NOT be eligible if...** - You have not completed the required diagnostic workup for primary aldosteronism - You have severe kidney or liver disease - You are pregnant - You cannot give informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURESelective adrenal artery embolization

Percutaneous selective adrenal artery embolization in patients with primary aldosteronism


Locations(1)

The First Affiliated Hospital of Chengdu Medical College

Chengdu, Sichuan, China

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NCT06228677


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