Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome
University of Aarhus
150 participants
Jan 8, 2024
OBSERVATIONAL
Conditions
Summary
100 women with karyotype verified TS, previously examined at 4 study visits during a 19-year period will be asked to participate in a 5th study visit. Healthy age-matched females will be included as controls in a ratio 2:1. The aim is to examine and quantify the cardiovascular and lymphatic system in women with TS. The investigators will study a possible causal mechanism between the known pathologic phenotype and alterations in these systems to understand, prevent or treat the life-threatening complications in TS.
Eligibility
Inclusion Criteria1
- Turner Syndrome
Exclusion Criteria2
- pregnancy
- contraindications for MRI
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Interventions
Skin, fat, and muscle biopsies will be obtained
Indocyanine green will be injected to evaluate the lymphatic system.
Locations(1)
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NCT06325618