RecruitingNot ApplicableNCT06411353

Blood Flow Conditions and Sounds in AVFs

The Relationship Between Blood Flow Conditions and Sounds in Arteriovenous Fistulae for Hemodialysis


Sponsor

Mario Negri Institute for Pharmacological Research

Enrollment

15 participants

Start Date

Mar 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a prospective non-pharmacological interventional study aimed at investigating the relationship between the blood flow condition and the arteriovenous fistula (AVF) sound, with the ultimate aim of predicting the AVF clinical, in patients with end-stage renal disease (ESRD) who require the creation of a vascular access for extracorporeal circulation.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study examines blood flow patterns and sounds in arteriovenous fistulas (AVFs) — surgically created connections between an artery and vein used for kidney dialysis. Researchers are using special imaging and sound analysis to better understand how these connections work and potentially predict problems before they happen. **You may be eligible if...** - You are between 18 and 90 years old - You have end-stage kidney disease and need a new vascular access (AVF) created, either because you are starting dialysis or preparing for it - Your first-choice treatment is a new forearm AVF **You may NOT be eligible if...** - There are medical reasons you cannot have an AVF created - You already have a failed AVF in the same arm - You have a pacemaker, metal implants, or other reasons you cannot have an MRI - You are already on dialysis through a catheter or graft - You are pregnant or have a life expectancy under 12 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTMRI acquisition

Non-contrast enhanced acquisitions will be performed using a whole-body MRI scanner operating at 1.5 Tesla or greater.

DIAGNOSTIC_TESTUS examination

A complete assessment of the AVF vessels is performed using advanced 3D US procedures.


Locations(1)

A.O. Papa Giovanni XXIII - U.O. Nefrologia e Dialisi

Bergamo, Bergamo, Italy

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NCT06411353


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