RecruitingNCT06706323

Depressive Symptoms After Cardiac Surgery

Predictive Modelling of Clinically Significant Depressive Symptoms After Coronary Artery Bypass Graft Surgery

Sponsor

Roland von Känel

Enrollment

300 participants

Start Date

Nov 25, 2024

Study Type

OBSERVATIONAL

Conditions

Quality of Life Cardiovascular Diseases Depression Anxiety Depressive Symptoms Postoperative Complications Heart Diseases Coronary Artery Disease Psychological Well-being Posttraumatic Stress Disorder

Summary

The primary goal of this project is to develop a predictive model for clinically significant depressive symptoms (CSDS) in patients undergoing coronary artery bypass graft (CABG) surgery, using pre- and perioperative data. CSDS occur in about 30 percent of CABG patients, which is four times higher than in the general population. These symptoms are linked to poor quality of life and increased morbidity and mortality. The aim is to create a model that can identify patients at risk for postoperative depression. This tool could help clinicians make informed decisions and take preventive measures to manage depression after surgery.

Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is tracking depressive symptoms in patients before and after heart bypass surgery (CABG) to better understand how and why some people develop depression after cardiac surgery, and to identify risk factors. **You may be eligible if...** - You are between 18 and 90 years old - You are scheduled for planned (elective) heart bypass surgery, with or without valve repair - You read and understand German sufficiently - You are willing and able to follow the study protocol **You may NOT be eligible if...** - You have significant cognitive impairment (based on a brief mental status test) - You have a serious non-cardiac illness likely to cause death within a year (e.g., metastatic cancer) - You currently have active psychotic symptoms or have had substance abuse problems in the past 6 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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