RecruitingNot ApplicableNCT06952348

HYPERtension Reduction Through WALKing Stairs Versus Brisk Walking

HYPERtension Reduction Through WALKing Stairs Versus Brisk Walking in Individuals With Increased Cardiometabolic Risk - The HYPERWALK Randomized Controlled Trial


Sponsor

Karolinska Institutet

Enrollment

450 participants

Start Date

Nov 27, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial investigates whether incorporating stair walking into daily routines improves physical health in adults at risk of lifestyle-related conditions such as hypertension, type 2 diabetes, and cardiovascular disease. Participants will be randomized into three groups: (1) stair walking combined with brisk walking, (2) brisk walking alone, and (3) a control group receiving standard lifestyle advice without specific exercise instructions, stratified by age (\<65 y/o, v \>=65) and site. The primary objective is to assess whether the combination of stair and brisk walking leads to greater reductions in systolic blood pressure compared to brisk walking alone or standard care. Secondary outcomes include changes in cardiometabolic risk factors. Participants in the stair walking group will be instructed to climb ≥250 steps per day (\~5.5 minutes/day or \~37.5 minutes/week), or complete an equivalent elevation via inclined slopes, along with ≥75 minutes of brisk walking per week. Those in the brisk walking group will walk ≥150 minutes per week. The control group will receive general lifestyle advice but no tailored physical activity goals or feedback. Participants in both active groups will aim to double their baseline activity levels. Physical activity will be continuously monitored using wearable devices. The active groups will receive personalized feedback and motivational support throughout the 6-month intervention period. If effective, this study may offer a simple, scalable, and low-cost intervention model for use in clinical and public health settings, emphasizing personalized goals, remote monitoring, and behavioral support.


Eligibility

Min Age: 35 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two exercise programs for people with high blood pressure (hypertension) who are also overweight and inactive — one group climbs stairs, and the other does brisk walking. Researchers want to find out which approach is more effective and practical for lowering blood pressure and improving overall cardiovascular health. **You may be eligible if...** - You are 35 years or older (male or female) - You have been diagnosed with high blood pressure (with or without blood pressure medications) - You have a BMI between 27 and 40 (overweight or obese) - You live a physically inactive or mostly sedentary lifestyle **You may NOT be eligible if...** - You have severe aortic valve disease, acute pulmonary embolism, active heart muscle inflammation (myocarditis or pericarditis), or suspected aortic dissection - You have very severe, uncontrolled high blood pressure (systolic above 180 mmHg or diastolic above 110 mmHg) - You have a recent serious systemic infection or fever Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALStair and brisk walking combined

See arms.

BEHAVIORALBrisk walking

See arms.

BEHAVIORALStandard care

See arms.


Locations(4)

Karolinska Universitetssjukhuset Huddinge

Stockholm, Sweden

Liljeholmen Primary Care Center

Stockholm, Sweden

Södersjukhuset

Stockholm, Sweden

Södertälje sjukhus

Stockholm, Sweden

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06952348


Related Trials