Evaluation of Molecular Hydrogen Supplementation to Enhance the Efficacy of Weight Loss Retreat in Overweight and Obese Adolescents
Evaluation of Molecular Hydrogen Supplementation to Enhance the Efficacy of Weight Loss Retreat in Overweight and Obese Adolescents. A Randomized, Double-blind, Parallel-group, Placebo-controlled Trial
Palacky University
60 participants
May 12, 2025
INTERVENTIONAL
Conditions
Summary
This randomized controlled trial evaluates whether molecular hydrogen supplementation enhances the effectiveness of a 4-week weight loss retreat in overweight and obese adolescents. Outcome measures include: body composition, physical status, blood samples (insulin sensitivity, lipid profiles, markers of oxidative stress and inflammation) and autonomic nervous system function.
Eligibility
Inclusion Criteria3
- Body mass index indicating overweight or obesity, as determined according to the World Health Organization's international percentile charts for children aged 5-19 years.
- Presence of a regular menstrual cycle in female participants.
- Signed informed consent from the legal representative.
Exclusion Criteria5
- High blood pressure.
- Dyslipoproteinemia.
- Cardio-respiratory disorders.
- Musculoskeletal disorders.
- Use of any medications regulating heart rhythm or the neurovegetative and hormonal system.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Hydrogen-rich water with molecular hydrogen concentration 1.2-1.6 ppm. No added sugar or preservatives.
Drinking water with molecular hydrogen concentration 0.0 ppm. No added sugar or preservatives.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06961110