RecruitingPhase 2NCT07312188

A Study of F182112 in the Treatment of Patients With Relapsed or Refractory Multiple Myeloma

A Phase II Study of F182112 Combined With Different Administration Regimens in Patients With Relapsed or Refractory Multiple Myeloma


Sponsor

Shandong New Time Pharmaceutical Co., LTD

Enrollment

90 participants

Start Date

Jul 2, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a single - arm, multi - cohort, open - label, multi - center Phase II clinical study. It aims to evaluate the efficacy and safety of F182112 combined with different administration regimens in patients with relapsed or refractory multiple myeloma.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests a new drug called F182112 in people with multiple myeloma — a type of blood cancer affecting plasma cells — whose cancer has come back or stopped responding to previous treatments. The study is particularly for those who have already received lenalidomide and a proteasome inhibitor. **You may be eligible if...** - You have confirmed multiple myeloma - Your previous treatment included both lenalidomide (for at least 2 cycles) and a proteasome inhibitor - Your cancer is measurable via blood or urine tests - Your overall health (ECOG 0–2) allows participation **You may NOT be eligible if...** - Your previous treatment included pomalidomide or you could not tolerate it - Your multiple myeloma has not returned or is not active - You have serious organ problems Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGF182112+P

F182112 + P

DRUGF182112+CD38

F182112+CD38


Locations(1)

Institute of Hematology & Blood Diseases Hospital

Tianjin, China

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NCT07312188


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