RecruitingNCT07415447

Cardiac Remodelling Following Endovascular Repair of the Aorta

Sponsor

Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa

Enrollment

40 participants

Start Date

Sep 1, 2025

Study Type

OBSERVATIONAL

Conditions

To assess the effects of endovascular aortic repair on cardiac morphology and function

Min Age: 18 Years

\- Patients over 18-year-old, with degenerative arch, descending thoracic or abdominal aortic aneurysms, penetrating aortic ulcers or intramural hematomas managed with total EVAR in elective setting.

Heart failure with an ejection fraction \<35 vs 50% or New York Heart Association (NYHA) class III and IV.
LV wall motion abnormality.
Moderate to severe valve disease.
History of (or expected within the study period) cardiac/aortic surgery.
Coronary artery disease.
Atrial fibrillation.
Congenital heart disease.
Connective tissue disorders.
Chronic kidney disease (eGFR \<30 mL/min/173 m2).
Moderate to severe pulmonary disease as indicate either by post bronchodilator FEV1 (%predicted) \<50% or Modified Medical Research Council Dyspnoea Scale (mMRC) 3-4.
CMR contraindications (non-compatible pacemakers and metal implants, and claustrophobia).

DIAGNOSTIC_TESTcardiac magnetic ressonance

In patients with aortic disease submitted to endovascular repair, will be studied through cardiac magnetic ressonance to evaluate cardiac function

Unidade Local de Saúde Santa Maria

Lisbon, Portugal

Unidade Local de Saúde de Santa Maria, E.P.E.

Lisbon, Portugal

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

NCT07415447