Aortic Disease Clinical Trials

28 recruitingLast updated: June 20, 2026

There are 28 actively recruiting aortic disease clinical trials across 18 countries. Studies span Not Applicable, Phase 4. Top locations include Roma, RM, Italy, Columbus, Ohio, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Aortic Disease Trials at a Glance

28 actively recruiting trials for aortic disease are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in Roma, Columbus, and Boston. Lead sponsors running aortic disease studies include Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Vascutek Ltd., and Centre Hospitalier Universitaire, Amiens.

Browse aortic disease trials by phase

Treatments under study

About Aortic Disease Clinical Trials

Looking for clinical trials for Aortic Disease? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Aortic Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Aortic Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 28 trials

Recruiting

Intervascular Post-Market Clinical Follow-Up (PMCF) Registry

Aortic DiseasesCarotid Artery DiseasesPeripheral Arterial Diseases
Intervascular1,200 enrolled4 locationsNCT07322913
Recruiting

Impact of Aortic Diseases on Quality of Life and Work Ability

Aortic Diseases
Fondazione Policlinico Universitario Agostino Gemelli IRCCS300 enrolled1 locationNCT07479186
Recruiting

Development of CIRC Technologies

Heart FailureCardiovascular DiseasesAtrial Fibrillation+7 more
The Cleveland Clinic1,000 enrolled1 locationNCT05654272
Recruiting

Accessing the Clarity and Acceptability of Recruitment Materials for a Study on Thoracic Aortic Disease Surveillance

Thoracic Aortic Disease
University of Nottingham30 enrolled1 locationNCT07574151
Recruiting
Not Applicable

INFLATE Study: Investigation of the Safety and Performance of a Novel PTV Balloon in Patients Undergoing TAVI for Severe Aortic Stenosis

Aortic Diseases
Biosensors Europe SA93 enrolled9 locationsNCT06816485
Recruiting

Use of Shockwave M5+/L6 IVL Catheter (Intravascular Lithotripsy) in Hostile and Calcified Iliac Access

Peripheral Arterial DiseaseAortic DiseasesAorto-Iliac Atherosclerosis
EndoCore Lab s.r.l.40 enrolled6 locationsNCT05880641
Recruiting

Cardiac Remodelling Following Endovascular Repair of the Aorta

Cardiac FailureAortic Disease
Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa40 enrolled2 locationsNCT07415447
Recruiting
Not Applicable

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

Aortic AneurysmAortic DiseasesAortic Aneurysm and Dissection+3 more
Vascutek Ltd.150 enrolled23 locationsNCT07078383
Recruiting

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

Aortic AneurysmAortic DissectionAortic Diseases
The University of Texas Health Science Center, Houston5,000 enrolled20 locationsNCT04005976
Recruiting

Effective Myocardial Protection Time of Del Nido Cardioplegia in Adult Cardiac Surgery

Myocardial IschemiaHeart Valve DiseasesAortic Diseases+3 more
Muhammet Talha Ceran, MD80 enrolled1 locationNCT07249424
Recruiting
Not Applicable

Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR

Aortic DiseasesAortic Stenosis (Treated With TAVI)
EnCompass Technologies, Inc.500 enrolled10 locationsNCT06689839
Recruiting
Not Applicable

Comparing Hypothermic Temperatures During Hemiarch Surgery

Thoracic Aortic Disease
Ottawa Heart Institute Research Corporation282 enrolled12 locationsNCT02860364
Recruiting
Phase 4

Liposomal Bupivacaine/Bupivacaine in Rectus Sheath Blocks Versus Ropivacaine in Rectus Sheath Blocks And Catheters

Aortoiliac occlusive diseaseAortic DiseasesAortic Aneurysm, Abdominal+1 more
Hartford Hospital14 enrolled1 locationNCT05972018
Recruiting

Management of Aorto-iliac Infection With BioIntegral Surgical No-React® Bovine Pericardial Xenografts

Aortic Diseases
Fondazione Policlinico Universitario Agostino Gemelli IRCCS30 enrolled1 locationNCT05777681
Recruiting

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

AneurysmAortic DiseasesAortic Arch+6 more
Vascutek Ltd.2,000 enrolled31 locationsNCT04545502
Recruiting
Not Applicable

Concordance of Three Imaging Methods by Dynamic CT, Contrast Ultrasound and CT Angiography in the Characterization of Endoleaks in Patients With an Aortic Endoprosthesis

Aortic Diseases
Centre Hospitalier Universitaire, Amiens69 enrolled1 locationNCT06318780
Recruiting

Mid- and Long-term Outcomes of Custom-made Aortic Devices

Thoracic Aortic AneurysmAortic Diseases
Fondazione Policlinico Universitario Agostino Gemelli IRCCS60 enrolled1 locationNCT05777460
Recruiting

Active Thoracic Compromised Distal LANding in TEvar

Thoracic Aortic AneurysmAortic Diseases
Fondazione Policlinico Universitario Agostino Gemelli IRCCS200 enrolled1 locationNCT06882967
Recruiting

International Multicenter Mycotic Aneurysm Aorto-iliac Study

Aortic DiseasesMycotic Aneurysm
Fondazione Policlinico Universitario Agostino Gemelli IRCCS40 enrolled1 locationNCT05777447
Recruiting

Gastrointestinal Dysfunction in Aortic Surgery Patients

Gastrointestinal dysfunctionSurgical ComplicationAortic Aneurysm+2 more
Instituto Nacional de Cardiologia Ignacio Chavez114 enrolled1 locationNCT06514170