RecruitingNCT07426146

Feasibility Effects of a Low-GI, High-fibre Diet in PCOS: a Prospective Cohort Study in Remote Yunnan

Sponsor

Shanghai First Maternity and Infant Hospital

Enrollment

56 participants

Start Date

Aug 10, 2025

Study Type

OBSERVATIONAL

Conditions

PCOS (Polycystic Ovary Syndrome)

Summary

This study aims to observe the effects of a 6-month, culturally-adapted low glycemic index-high fiber (LGI-HF) dietary on IR, androgen levels, and menstrual regularity among women with PCOS in remote areas of Yunnan Province. We hypothesize that a nutritional strategy designed for high-carbohydrate dietary habits while balancing feasibility and adherence can significantly improve patients' metabolic and reproductive parameters, thereby providing practical evidence-based guidance for long-term PCOS management in resource-limited settings

Eligibility

Sex: FEMALEMin Age: 19 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at whether a low-glycaemic index (low-GI), high-fibre diet can improve symptoms of polycystic ovary syndrome (PCOS) in women living in a remote region of Yunnan, China. PCOS is a hormonal condition that can affect periods, fertility, and metabolism. **You may be eligible if...** - You have been diagnosed with PCOS based on standard diagnostic criteria - Your BMI is 24 kg/m² or higher - Your weight has been stable for the past 3 months - You are willing to maintain your usual physical activity during the study - You live within the designated study area and will remain there for at least 6 months **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have type 1 or type 2 diabetes - You have thyroid disease, high prolactin, congenital adrenal hyperplasia, Cushing's syndrome, or other hormonal conditions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERlow glycemic index-high fiber

This was a prospective, single-center intervention study designed to evaluate the feasibility and metabolic/reproductive effects of an adaptive low glycemic index, high-fiber diet (LGI-HF) on women with polycystic ovary syndrome (PCOS) residing in remote mountainous areas of Yunnan, China. The intervention lasted 24 weeks, with assessments at baseline (week 0), mid-intervention (week 12), and end of intervention (week 24)

Locations(2)

Department of Gynaecology, Gengma People's Hospital

Gengma County, Yunnan, China

Gengma People's Hospital

Lincang, Yunnan, China

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NCT07426146

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