Connective Tissue Disease Clinical Trials

6 recruiting

Connective Tissue Disease Trials at a Glance

37 actively recruiting trials for connective tissue disease are listed on ClinicalTrialsFinder across 6 cities in 28 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in Bonn, Durham, and Beijing. Lead sponsors running connective tissue disease studies include Institute of Hematology & Blood Diseases Hospital, China, University of Bonn, and Bastiaan Driehuys.

Browse connective tissue disease trials by phase

Treatments under study

About Connective Tissue Disease Clinical Trials

Looking for clinical trials for Connective Tissue Disease? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Connective Tissue Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Connective Tissue Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 37 trials

Recruiting
Not Applicable

Early Recognition of Progressive Lung Fibrosis in Systemic Rheumatic Diseases

Interstitial Lung DiseaseConnective Tissue Diseases
Fondazione Policlinico Universitario Agostino Gemelli IRCCS200 enrolled1 locationNCT07541638
Recruiting
Phase 2

A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

Progressive Pulmonary FibrosisInterstitial Lung DiseasePulmonary Fibrosis+4 more
Avalyn Pharma Inc.375 enrolled152 locationsNCT06329401
Recruiting
Early Phase 1

Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases

Systemic Lupus Erythematosus (SLE)Rheumatic DiseasesPediatric Rheumatological Condition (i.e., Arthritis, SLE, Kawasaki's Disaese)+1 more
The Children's Hospital of Zhejiang University School of Medicine36 enrolled1 locationNCT07490041
Recruiting
Not Applicable

Impact of Capillaroscopy in the Investigation of Diffuse Interstitial Pneumonias

Interstitial Lung DiseaseConnective Tissue Diseases
University Hospital, Bordeaux48 enrolled1 locationNCT07283081
Recruiting
Not Applicable

Impact of Capillaroscopy on the Management of Undifferentiated Connective Tissue Disease

Undifferentiated Connective Tissue Diseases
CHU de Quebec-Universite Laval40 enrolled1 locationNCT06399822
Recruiting

Heart Institute Biobank & Registry for Adult Congenital Heart Disease and Related Disorders

Pulmonary HypertensionConnective Tissue DiseaseAdult Congenital Heart Disease+1 more
Children's Hospital Medical Center, Cincinnati5,000 enrolled1 locationNCT07477197
Recruiting
Phase 2

129 Xenon MRI as a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial HypertensionConnective Tissue DiseasesIdiopathic Pulmonary Arterial Hypertension+1 more
Bastiaan Driehuys20 enrolled1 locationNCT06104228
Recruiting

Undifferentiated Connective Tissue Disease Registry

Undifferentiated Connective Tissue Disease
Hospital for Special Surgery, New York100 enrolled1 locationNCT02234388
Recruiting

Rheumatology Patient Registry and Biorepository

Rheumatoid ArthritisLyme DiseaseSarcoidosis+17 more
Yale University5,000 enrolled1 locationNCT04402086
Recruiting
Not Applicable

Ganglion Resection Effectiveness Trial

Connective Tissue DiseaseWrist GanglionGanglion+2 more
Tampere University Hospital220 enrolled4 locationsNCT07162415
Recruiting
Phase 1

CAR T-cell Therapy Targeting CD19 and BCMA(QT-019C) in Patients With Relapse/Refractory Autoimmune Diseases

ANCA Associated Vasculitis (AAV)SLE - Systemic Lupus ErythematosusSSc-Systemic Sclerosis+3 more
Institute of Hematology & Blood Diseases Hospital, China12 enrolled1 locationNCT07315087
Recruiting
Not Applicable

Creating Health Course Study for People With Rheumatological Conditions

Rheumatoid ArthritisPsoriatic ArthritisSystemic Lupus Erythematosus+2 more
Terry L. Wahls200 enrolled1 locationNCT07180537
Recruiting
Phase 4

A Study to Test Tetrandrine Tablets for Connective Tissue Disease-Related Lung Disease

Interstitial Lung Disease (ILD)Connective Tissue Disease-associated Interstitial Lung Disease
Peking University Third Hospital100 enrolled1 locationNCT07319598
Recruiting
Phase 3

A Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis Bullosa

Skin DiseasesEpidermolysis BullosaConnective Tissue Disease+7 more
Chiesi Farmaceutici S.p.A.6 enrolled6 locationsNCT06917690
Recruiting
Phase 3

A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)

Connective Tissue Diseases
GlaxoSmithKline514 enrolled10 locationsNCT06716606
Recruiting

Rutgers University Study of the Genetics of Pulmonary Hypertension

Pulmonary HypertensionPulmonary Arterial HypertensionPulmonary Arterial Hypertension of Congenital Heart Disease+5 more
Rutgers, The State University of New Jersey10,000 enrolled1 locationNCT07217522
Recruiting

Clinical Features and Prognosis of Takayasu's Arteritis With Pulmonary Arteries Involvement

Takayasu Arteritis With Pulmonary Artery InvolvementPulmonary Arterial Hypertension Associated With Connective Tissue Disease
China-Japan Friendship Hospital150 enrolled1 locationNCT07184814
Recruiting

Radiologic Features of Rheumatoid Arthritis Interstitial Lung Disease at Chest High Resolution Computed Tomography

Connective Tissue Disease (CTD)Interstitial Lung Disease Due to Systemic Disease (Disorder)Idiopathic Pulmonary Fibrosis (IPF)+1 more
Azienda Unita Sanitaria Locale di Piacenza500 enrolled5 locationsNCT07174102
Recruiting
Phase 2

Intralesional Injection of STS in Treatment of Calcinosis

DermatomyositisSystemic Sclerosis (SSc)Mixed Connective Tissue Disease (MCTD)+1 more
Robyn T. Domsic, MD, MPH20 enrolled1 locationNCT06672822
Recruiting
Not Applicable

Clinical Study on the Safety and Efficacy of CD19-BCMA CAR-T Cell Therapy for Connective Tissue Diseases

Connective Tissue Diseases
Guangzhou Bio-gene Technology Co., Ltd20 enrolled1 locationNCT07152223