Phase 3 ache Clinical Trials

17 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 117 of 17 trials

Recruiting
Phase 2Phase 3

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Metastatic Pancreatic Ductal AdenocarcinomaCachexia
Pfizer982 enrolled129 locationsNCT06989437
Recruiting
Phase 2Phase 3

Visugromab in Cachexia International Trial

Cancer-associated Cachexia
CatalYm GmbH518 enrolled7 locationsNCT07112196
Recruiting
Phase 3

Efficacy of Sphenopalatine Block Compared to Blood Patch in the Management of Post-dural Puncture Headaches

Post Dural puncture headache.PDPH
University Hospital, Clermont-Ferrand80 enrolled1 locationNCT07354464
Recruiting
Phase 3

Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches

Chronic Daily Headache
University Health Network, Toronto56 enrolled2 locationsNCT05306899
Recruiting
Phase 2Phase 3

Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache

SAH (Subarachnoid Hemorrhage)Headache
University of California, Davis40 enrolled1 locationNCT06621329
Recruiting
Phase 3

Repeated GON Injections in CCH

Cluster Headache
Leiden University Medical Center50 enrolled2 locationsNCT05324748
Recruiting
Phase 3

The Nordic Chronic Migraine Trial of CGRP Monoclonal Antibody and Onabotulinumtoxin A Dual Therapy Compared to CGRP mAbs Monotherapy

MigraineChronic Migraine, Headache
Oslo University Hospital450 enrolled6 locationsNCT07040813
Recruiting
Phase 3

Idebenone for the Preventive Treatment of Migraine

Migraine DisordersHeadache Disorders
Second Affiliated Hospital, School of Medicine, Zhejiang University180 enrolled1 locationNCT04151472
Recruiting
Phase 3

Safety and Efficacy of Botulinum Toxin A in Patients With Posttraumatic Headache

Posttraumatic Headache
Danish Headache Center80 enrolled1 locationNCT06839118
Recruiting
Phase 2Phase 3

Adrenaline Nasal Pack vs Xylometazoline Nasal Drops During Nasotracheal Intubation

Nasal BleedingNasotracheal Intubation
Shaheed Mohtarma Benazir Bhutto Institue of Trauma70 enrolled1 locationNCT06801522
Recruiting
Phase 3

Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Cluster Headache

Cluster Headache
Norwegian University of Science and Technology112 enrolled5 locationsNCT03944876
Recruiting
Phase 3

Olanzapine for Cancer Related Anorexia-cachexia Syndrome

AnorexiaCachexia
Mahidol University138 enrolled2 locationsNCT06517199
Completed
Phase 3Phase 4

A double-blind randomised controlled study to evaluate the effectiveness of orally-dosed Palmitoylethanolamide (PEA) compared to ibuprofen for reducing pain severity and duration of headaches in healthy participants aged 18 years and older.

Headache
RDC Global Pty Ltd80 enrolled1 locationACTRN12618000294257
Completed
Phase 3Phase 4

The Effect of Intranasal Dexmedetomidine Premedication on the Minimum Alveolar Concentration of Sevoflurane for tracheal intubation in children

inhalation induction of anesthesia and tracheal intubation in children
Yusheng Yao90 enrolled1 locationACTRN12613000679785
Recruiting
Phase 3Phase 4

Exogenous Melatonin to Improve Sleep in Critically Ill Patients

Poor sleep in tracheostomised ICU patients.
The Alfred60 enrolled1 locationACTRN12610000008022
Not Yet Recruiting
Phase 3

Inadvertant dural puncture in labour: Intrathecal Catheter versus Epidural (The ICE Pilot Study)

Epidural blood patchPostdural puncture headache
Allan M Cyna12 enrolled1 locationACTRN12608000009314
Completed
Phase 3Phase 4

Comparison between single dose oral prednisolone and oral dexamethasone in the treatment of croup: a randomised, double-blind clinical trial.

Croup (laryngotracheobronchitis)
Mater Childrens' Hospital Department of Paediatric Emergency Medicine100 enrolled1 locationACTRN12605000447651