Phase 1 Acute Myeloid Leukemia, in Relapse Clinical Trials

11 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 111 of 11 trials

Recruiting
Phase 1

Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, RefractoryRefractory/Relapse Acute Myeloid Leukemia
Keystone Nano, Inc15 enrolled1 locationNCT04716452
Recruiting
Phase 1

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

Acute Myeloid LeukemiaMyeloid SarcomaAcute Myeloid Leukemia, in Relapse+7 more
Kura Oncology, Inc.420 enrolled44 locationsNCT05735184
Recruiting
Phase 1

A Study of CD371-YSNVZIL-18 CAR T Cells in People With Acute Myeloid Leukemia

Acute Myeloid LeukemiaAcute Myeloid Leukemia, in RelapseRefractory Acute Myeloid Leukemia+1 more
Memorial Sloan Kettering Cancer Center15 enrolled7 locationsNCT06017258
Recruiting
Phase 1

Venetoclax to Augment Epigenetic Modification and Chemotherapy

Acute Myeloid Leukemia, in Relapse
Medical College of Wisconsin40 enrolled1 locationNCT05317403
Recruiting
Phase 1

Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid LeukemiaAcute Myeloid Leukemia, in RelapseRefractory Acute Myeloid Leukemia
Terrence J Bradley, MD18 enrolled1 locationNCT05597306
Recruiting
Phase 1

Safety of MT-401-OTS in Patients With Relapsed AML or MDS

MDSAcute Myeloid Leukemia, in Relapse
Marker Therapeutics, Inc.40 enrolled3 locationsNCT06552416
Recruiting
Phase 1Phase 2

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

Acute Myeloid Leukemia, in Relapse
ARCE Therapeutics, Inc.49 enrolled3 locationsNCT06680752
Recruiting
Phase 1

Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies

Acute Myeloid Leukemia, in Relapse
AvenCell Europe GmbH80 enrolled11 locationsNCT05949125
Recruiting
Phase 1

A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia, in Relapse
Bio-Path Holdings, Inc.48 enrolled4 locationsNCT05190471
Recruiting
Phase 1

Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)

Acute Myeloid Leukemia, in Relapse
Oryzon Genomics S.A.50 enrolled13 locationsNCT05546580
Recruiting
Phase 1

Treatment With ABT-199 (Venetoclax) and Purine Analogues in Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia, in Relapse
University Hospital, Antwerp10 enrolled2 locationsNCT05506332