Phase 1 Acute Myeloid Leukemia, in Relapse Clinical Trials
17 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–17 of 17 trials
Recruiting
Phase 1
A Study of Natural Killer Cells in Combination With Atezolizumab in People With Acute Myelogenous Leukemia
Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, Refractory
Memorial Sloan Kettering Cancer Center18 enrolled7 locationsNCT07011004
Recruiting
Phase 1
A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS
Acute Myeloid Leukemia (AML)Acute Myeloid Leukemia, in RelapseMyelodysplastic Syndrome With Excess Blasts+2 more
Apollo Therapeutics Ltd100 enrolled9 locationsNCT06372717
Recruiting
Phase 1
Adoptive T Cell Therapy With DC/AML Fusion Vaccine Plus Decitabine and Venetoclax in AML
Acute Myeloid LeukemiaAcute Myeloid Leukemia, in Relapse
David Avigan30 enrolled1 locationNCT07374029
Recruiting
Phase 1
Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, RefractoryRefractory/Relapse Acute Myeloid Leukemia
Keystone Nano, Inc15 enrolled1 locationNCT04716452
Recruiting
Phase 1
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
Acute Myeloid LeukemiaMyeloid SarcomaAcute Myeloid Leukemia, in Relapse+7 more
Kura Oncology, Inc.420 enrolled44 locationsNCT05735184
Recruiting
Phase 1
A Study of CD371-YSNVZIL-18 CAR T Cells in People With Acute Myeloid Leukemia
Acute Myeloid LeukemiaAcute Myeloid Leukemia, in RelapseRefractory Acute Myeloid Leukemia+2 more
Memorial Sloan Kettering Cancer Center15 enrolled7 locationsNCT06017258
Recruiting
Phase 1
Venetoclax to Augment Epigenetic Modification and Chemotherapy
Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, Refractory
Medical College of Wisconsin40 enrolled1 locationNCT05317403
Recruiting
Phase 1
Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Acute Myeloid LeukemiaAcute Myeloid Leukemia, in RelapseRefractory Acute Myeloid Leukemia
Terrence J Bradley, MD18 enrolled1 locationNCT05597306
Recruiting
Phase 1
PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML
Acute Myeloid LeukemiaAcute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, Refractory
Seattle Children's Hospital18 enrolled1 locationNCT05105152
Recruiting
Phase 1
Safety of MT-401-OTS in Patients With Relapsed AML or MDS
MDSAcute Myeloid Leukemia, in Relapse
Marker Therapeutics, Inc.40 enrolled3 locationsNCT06552416
Recruiting
Phase 1Phase 2
Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS
Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, RefractoryMDS (Myelodysplastic Syndrome)
ARCE Therapeutics, Inc.49 enrolled3 locationsNCT06680752
Recruiting
Phase 1Phase 2
AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, RefractoryMyelodysplastic Syndrome/Acute Myeloid Leukemia
AB Science78 enrolled10 locationsNCT05211570
Recruiting
Phase 1
Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies
Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, Refractory
AvenCell Europe GmbH80 enrolled11 locationsNCT05949125
Recruiting
Phase 1
A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)
Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, Refractory
Bio-Path Holdings, Inc.48 enrolled4 locationsNCT05190471
Recruiting
Phase 1
Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)
Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, Refractory
Oryzon Genomics S.A.50 enrolled13 locationsNCT05546580
Recruiting
Phase 1Phase 2
Administration of Anti Tim-3/CD123 CAR-T Cell Therapy in Relapsed and Refractory Acute Myeloid Leukemia (rr/AML)
Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, Refractory
Xuzhou Medical University20 enrolled1 locationNCT06125652
Recruiting
Phase 1
Treatment With ABT-199 (Venetoclax) and Purine Analogues in Relapsed/Refractory Acute Myeloid Leukemia
Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia, Refractory
University Hospital, Antwerp10 enrolled2 locationsNCT05506332