Addiction Clinical Trials

109 recruitingLast updated: June 18, 2026

There are 109 actively recruiting addiction clinical trials across 23 countries. Studies span Not Applicable, Phase 2, Phase 4, Early Phase 1, Phase 3, Phase 1. Top locations include Baltimore, Maryland, United States, Nantes, France, Toronto, Ontario, Canada. Updated daily from ClinicalTrials.gov.


Addiction Trials at a Glance

109 actively recruiting trials for addiction are listed on ClinicalTrialsFinder across 6 cities in 23 countries. The largest study group is Not Applicable with 49 trials, with the heaviest enrollment activity in Baltimore, Nantes, and Toronto. Lead sponsors running addiction studies include Saglik Bilimleri Universitesi, Centre Hospitalier Charles Perrens, Bordeaux, and Central Institute of Mental Health, Mannheim.

Browse addiction trials by phase

Treatments under study

About Addiction Clinical Trials

Looking for clinical trials for Addiction? There are currently 38 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Addiction trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Addiction clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 109 trials

Recruiting
Not Applicable

Neuroimaging of Adolescent Cannabis Use Treatment

Cannabis withdrawalSubstance Use DisordersCannabis Use+23 more
Indiana University80 enrolled1 locationNCT07340554
Recruiting
Early Phase 1

Addictive Threshold of Nicotine

smoking addiction
Yale University45 enrolled1 locationNCT06096714
Recruiting
Not Applicable

Efficiency of Prevention Program Dedicated to Addictive Behaviors (PREVENTURE) of Vulnerable Teenagers

Addiction, AlcoholAddiction, Substance
University Hospital, Brest700 enrolled5 locationsNCT04599270
Recruiting

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

Drug addictionOpioid-Related Disorders
National Institute on Drug Abuse (NIDA)150 enrolled1 locationNCT03745339
Recruiting
Not Applicable

Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of Alcohol Use Disorder (AUD)

AlcoholismAlcohol Use DisorderAlcohol Dependence+3 more
Brainsway186 enrolled9 locationsNCT07216872
Recruiting

Paraphilic Disorders and Other Conditions With Risk for Sexual Violence: a Case-control Study

parasomniaParaphilic DisordersSexual Addiction
Region Stockholm240 enrolled1 locationNCT05861752
Recruiting

Pain and Upper Extremity Function in Smartphone and Digital Game Addiction

Addiction
Istinye University60 enrolled1 locationNCT07573345
Recruiting
Phase 2

Semaglutide Therapy for Alcohol Reduction (STAR)

Alcohol Use DisorderAddiction
National Institute on Drug Abuse (NIDA)80 enrolled1 locationNCT06015893
Recruiting

Smartphone Addiction, Posture and Breathing Control in University Students

Postural DisordersDysfunctional BreathingSmartphone Addiction
Istanbul Medeniyet University300 enrolled1 locationNCT07615322
Recruiting
Not Applicable

Behavioral and Functional Task Development, Implementation, and Testing

AlcoholismAlcohol DrinkingAlcohol Use Disorder+2 more
National Institute on Alcohol Abuse and Alcoholism (NIAAA)400 enrolled1 locationNCT02108054
Recruiting
Not Applicable

Ultra Crave: An Investigation of Ultra-Processed Food

Food Addiction
University of Michigan210 enrolled1 locationNCT06044285
Recruiting
Not Applicable

Metabolome and Gut Microbiome Changes During Smoking Cessation in Long-term Drug Therapy in a Therapeutic Community

healthy adult participantsSubstance Use Disorder (SUD)Alcohol Use Disorder (AUD)+1 more
Sigmund Freud PrivatUniversitat150 enrolled3 locationsNCT06803706
Recruiting

NLP Analysis of Weekly Narratives for Dynamic Clinical Assessment in SUD

AnxietyEmotional DysregulationSubstance Use Disorder (SUD)+2 more
Lauro Gutiérrez Castro35 enrolled1 locationNCT07595614
Recruiting

Measuring Communal Coping in Dual-smoking Couples Making a Quit Attempt

Quitting smokingSmoking CessationSmoking, Cigarette+3 more
University of Colorado, Denver250 enrolled1 locationNCT07553962
Recruiting
Phase 2

Effect of Semaglutide on Cannabis Use in Adults With Cannabis Use Disorder

Cannabis Use DisorderCannabis DependenceCannabis Abuse+2 more
Anders Fink-Jensen, MD, DMSci100 enrolled1 locationNCT07523633
Recruiting

Neurotrophic Factors, Impulsivity, and Reward Sensitivity in Children With Internet Gaming Disorder

Internet Gaming DisorderInternet Addiction
Istanbul Saglik Bilimleri University120 enrolled1 locationNCT07590180
Recruiting
Phase 3

Semaglutide for Smoking Cessation in Patients With Diabetes

Diabetes Mellitus, Type 2Tobacco DependenceNicotine Addiction
Ottawa Heart Institute Research Corporation100 enrolled1 locationNCT07059377
Recruiting
Not Applicable

HABITS Study (Helping Addiction by Individualized Therapeutic Stimulation): Pilot Trial of Deep Brain Stimulation Guided By Stereoelectroencephalography for Treatment-Refractory Substance Use Disorders

Substance Use Disorder (SUD)Addiction
Centre for Addiction and Mental Health10 enrolled1 locationNCT06973512
Recruiting

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Healthy VolunteerTobacco Use DisorderMigraine+8 more
Yale University200 enrolled2 locationsNCT06624137
Recruiting

Health Surveillance at Constructor University Bremen (CUB) and Among HAW-Hamburg Employees

AnxietyPsychological StressHealth Behavior+12 more
Jacobs University Bremen gGmbH363 enrolled2 locationsNCT06899308