Adenoid Cystic Carcinoma Clinical Trials

19 recruitingLast updated: June 17, 2026

There are 19 actively recruiting adenoid cystic carcinoma clinical trials across 8 countries. Studies span Phase 2, Phase 1, Not Applicable, Early Phase 1. Top locations include Houston, Texas, United States, Boston, Massachusetts, United States, New York, New York, United States. Updated daily from ClinicalTrials.gov.


Adenoid Cystic Carcinoma Trials at a Glance

19 actively recruiting trials for adenoid cystic carcinoma are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Phase 2 with 11 trials, with the heaviest enrollment activity in Houston, Boston, and New York. Lead sponsors running adenoid cystic carcinoma studies include Glenn J. Hanna, Eye & ENT Hospital of Fudan University, and Dana-Farber Cancer Institute.

Browse adenoid cystic carcinoma trials by phase

Treatments under study

About Adenoid Cystic Carcinoma Clinical Trials

Looking for clinical trials for Adenoid Cystic Carcinoma? There are currently 15 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Adenoid Cystic Carcinoma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Adenoid Cystic Carcinoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting
Phase 2

Epirubicin Interventional Chemotherapy for Sinonasal Adenoid Cystic Carcinoma (SNACC): A Prospective Study

Adenoid Cystic CarcinomaSinonasal CarcinomaEpirubicin
Eye & ENT Hospital of Fudan University100 enrolled1 locationNCT07320508
Recruiting
Phase 2

A Study of Becotatug Vedotin (MRG003) Combined With Epirubicin as Neoadjuvant Therapy for EGFR-Positive, Unresectable Recurrent Sinonasal Adenoid Cystic Carcinoma

Adenoid Cystic CarcinomaSinonasal Carcinoma
Eye & ENT Hospital of Fudan University40 enrolled1 locationNCT07522879
Recruiting
Phase 2

Phase II Trial of Puxitatug Samrotecan (AZD8205) in Advanced, Recurrent or Metastatic (R/M) Aggressive Adenoid Cystic Carcinoma Subtype I (ACC-I)

Adenoid Cystic Carcinoma
M.D. Anderson Cancer Center28 enrolled1 locationNCT07162480
Recruiting
Phase 2

Agnostic Therapy in Rare Solid Tumors

Cancer of Unknown PrimarySoft Tissue SarcomaCholangiocarcinoma+38 more
Instituto do Cancer do Estado de São Paulo28 enrolled8 locationsNCT06638931
Recruiting
Phase 1

A Study of XMT-1660 in Participants With Solid Tumors

Breast CancerTriple-Negative Breast CancerOvarian Cancer+4 more
Mersana Therapeutics319 enrolled26 locationsNCT05377996
Recruiting

A Multi-omics Approach to Disclose Progression and Underlying Biology of Head and Neck Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma of the Salivary GlandAdenoid Cystic Carcinoma of the Head and Neck
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano114 enrolled1 locationNCT07507578
Recruiting
Phase 2

A Study of Enfortumab Vedotin in People With Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma
Memorial Sloan Kettering Cancer Center34 enrolled7 locationsNCT06891560
Recruiting
Phase 1Phase 2

Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

Adenoid Cystic CarcinomaMetastatic Adenoid Cystic CarcinomaRecurrent Adenoid Cystic Carcinoma
Remix Therapeutics100 enrolled8 locationsNCT06118086
Recruiting
Not Applicable

Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck

Tongue CancerRecurrent Adenoid Cystic Carcinoma of the Oral CavityRecurrent Mucoepidermoid Carcinoma of the Oral Cavity+48 more
Ohio State University Comprehensive Cancer Center600 enrolled1 locationNCT01473784
Recruiting
Early Phase 1

Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers

Head and Neck CancerSquamous Cell Carcinoma of Head and NeckSalivary Gland Cancer+1 more
Brigham and Women's Hospital30 enrolled2 locationsNCT05553782
Recruiting
Phase 1Phase 2

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

Esophageal CancerPancreatic CancerHead and Neck Squamous Cell Carcinoma (HNSCC)+22 more
VM Oncology, LLC242 enrolled15 locationsNCT03556228
Recruiting
Phase 1

Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

Colorectal, CancerAdenoid Cystic Carcinoma
Rgenta Therapeutics Inc105 enrolled10 locationsNCT06462183
Recruiting
Not Applicable

Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

Adenoid Cystic CarcinomaMetastatic Adenoid Cystic Carcinoma
Dana-Farber Cancer Institute32 enrolled5 locationsNCT04883671
Recruiting
Phase 1

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

Uveal MelanomaNeuroendocrine TumorsGastrointestinal Stromal Tumors+4 more
Novelty Nobility, Inc.67 enrolled5 locationsNCT06805825
Recruiting
Phase 2

A Phase 2 Trial of Ivonescimab for Patients With Advanced, Metastatic Salivary Gland Cancers

Salivary Gland CancerAdvanced Salivary Gland CarcinomaAdenoid Cystic Carcinoma+1 more
Glenn J. Hanna35 enrolled2 locationsNCT06805617
Recruiting
Phase 1Phase 2

CB-103 With Either Lenvatinib or Abemaciclib in Patients With NOTCH ACC

Adenoid Cystic CarcinomaMetastatic Adenoid Cystic CarcinomaRecurrent Adenoid Cystic Carcinoma
Glenn J. Hanna32 enrolled1 locationNCT05774899
Recruiting
Phase 2

Clinical Trial of HG146 Administered to Participants with Adenoid Cystic Carcinoma

Head and Neck CancerAdenoid Cystic Carcinoma
HitGen Inc.140 enrolled1 locationNCT06781567
Recruiting
Phase 2

Adenoid Cystic Carcinoma and Carbon Ion Only Irradiation

Adenoid Cystic Carcinoma
Heidelberg University314 enrolled1 locationNCT04214366
Recruiting
Not Applicable

Randomized Carbon Ions vs Standard Radiotherapy for Radioresistant Tumors

Malignant Tumors as Chordoma, Adenoid Cystic Carcinoma and Sarcoma
Hospices Civils de Lyon250 enrolled21 locationsNCT02838602