Adolescence Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Adolescence clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 27 trials

Recruiting
Phase 1Phase 2

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

Type 1 DiabetesType 1 Diabetes MellitusType 1 Diabetes Mellitis+7 more
COUR Pharmaceutical Development Company, Inc.72 enrolled31 locationsNCT06783309
Recruiting

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

Insulin ResistanceCognitive DeclineInflammation+8 more
Washington University School of Medicine117 enrolled2 locationsNCT05277558
Recruiting
Not Applicable

The Prism Conformity Trial for Post-Traumatic Stress Disorder in Adolescents

Post-Traumatic Stress Disorder in Adolescence
GrayMatters Health Ltd.45 enrolled1 locationNCT06854328
Recruiting
Not Applicable

Integrating Project YES! With WHO-Endorsed Mental Health Approaches Among Youth Living With HIV

AnxietyHIV (Human Immunodeficiency Virus)Mental Health+2 more
Johns Hopkins Bloomberg School of Public Health400 enrolled1 locationNCT07221201
Recruiting
Not Applicable

Parent-Based Treatment for Adolescent Anxiety

Anxiety Disorder of Adolescence
Yale University108 enrolled1 locationNCT07219992
Recruiting
Not Applicable

Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep to Reward- and Stress-Related Brain Function

Depression in Adolescence
University of Oregon150 enrolled1 locationNCT05691439
Recruiting
Not Applicable

Wise Intervention for Reducing Aggressive Behaviors and Promoting Prosocial Behaviors Toward LGB-TNB Individuals

AggressionAdolescence
University of Deusto1,000 enrolled1 locationNCT07212283
Recruiting
Not Applicable

Brief Videos Delivered by Text Messages as a Public Health Intervention for PTSD in Youth

Post Traumatic Stress Disorder (PTSD)Post-Traumatic Stress Disorder in AdolescencePost-Traumatic Stress Disorder in Youth
IWK Health Centre98 enrolled1 locationNCT07165782
Recruiting
Not Applicable

Promoting Mental Health Among At-risk Adolescents in Malaysia

AnxietyDepression in Adolescence
University of Roehampton428 enrolled5 locationsNCT07138664
Recruiting
Not Applicable

Exercise Facilitation of Adolescent Fear Extinction, Frontolimbic Circuitry, and Endocannabinoids

Adolescence
Wayne State University174 enrolled1 locationNCT06297278
Recruiting
Not Applicable

Neuro-affective Response to Light in Depressed Adolescents and Young Adults

Depression in AdultsDepression in Adolescence
University of Pittsburgh80 enrolled1 locationNCT05712772
Recruiting
Not Applicable

CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD

Obsessive-Compulsive DisorderCognitive Behavioral TherapyObsessive-Compulsive Disorder in Children+1 more
Baylor College of Medicine200 enrolled1 locationNCT05609916
Recruiting
Not Applicable

Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD

Obsessive Compulsive Disorder (OCD)Panic DisorderGeneralized Anxiety Disorder (GAD)+6 more
Baylor College of Medicine174 enrolled1 locationNCT07024758
Recruiting
Not Applicable

Telehealth Behavioral Activation for Teens

DepressionSuicide and Self-harmDepression in Adolescence+3 more
Baylor College of Medicine250 enrolled1 locationNCT06273995
Recruiting
Phase 2

Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders

AnxietyTuberous SclerosisFragile X Syndrome+14 more
Holland Bloorview Kids Rehabilitation Hospital130 enrolled8 locationsNCT06081348
Recruiting
Not Applicable

Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents

DepressionSuicideMajor Depressive Disorder+6 more
University of Alabama at Birmingham240 enrolled2 locationsNCT05437588
Recruiting
Not Applicable

Better Sleep Study

Depression in AdolescenceDelayed Sleep Phase
University of California, San Francisco200 enrolled1 locationNCT06139861
Recruiting

Inflammatory and Glutamatergic Mechanisms of Sustained Threat in Adolescents With Depression

Depression in Adolescence
University of California, Los Angeles160 enrolled1 locationNCT05329441
Recruiting
Not Applicable

Mindfulness-Based fMRI Neurofeedback for Depression

RuminationDepression in Adolescence
Columbia University90 enrolled2 locationsNCT05617495
Recruiting
Not Applicable

Empowering Perinatal Adolescents Through Writing

PTSD - Post Traumatic Stress DisorderPTSD and Trauma-related SymptomsPost-Traumatic Stress Disorder in Adolescence+1 more
University of Texas Southwestern Medical Center30 enrolled1 locationNCT06771817