Phase 4 Age Clinical Trials

31 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 31 trials

Recruiting
Phase 4

Serotonin-norepinephrine Reuptake Inhibitor in Prophylaxis of Depression Following Fragility Fractures

Depression in Old AgeFragility Fracture
Wake Forest University Health Sciences100 enrolled1 locationNCT05851898
Recruiting
Phase 4

Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer

Breast CancerEsophageal CancerMetastatic Gastric Cancer
University of Michigan Rogel Cancer Center22 enrolled1 locationNCT05183126
Recruiting
Phase 4

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain
City of Hope Medical Center10 enrolled1 locationNCT05376878
Recruiting
Phase 4

Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial

Metastatic Bladder Urothelial CarcinomaStage IV Bladder Cancer AJCC v8Metastatic Renal Pelvis and Ureter Urothelial Carcinoma+4 more
Mayo Clinic75 enrolled1 locationNCT06764095
Recruiting
Phase 4

A Study of Revaree Plus in People With Breast Cancer

Breast CancerStage III Breast CancerStage I Breast Cancer+5 more
Memorial Sloan Kettering Cancer Center60 enrolled7 locationsNCT07042581
Recruiting
Phase 4

Effect of HSD3B1 (1245C) Gene Mutation on Treatment of Stage I-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8+2 more
University of Washington68 enrolled1 locationNCT05183828
Recruiting
Phase 4

Actualities in Procedural Sedation: Remimazolam

ASA Class III/IV PatientsCOPD III/IVAge 65 and Older+1 more
Iuliu Hatieganu University of Medicine and Pharmacy200 enrolled1 locationNCT07362173
Recruiting
Phase 4

Blood Pressure Control With Thiazide Diuretics in Peritoneal Dialysis Patients

HypertensionPeritoneal DialysisEnd Stage Kidney Disease (ESRD)
Chinese University of Hong Kong40 enrolled1 locationNCT07271420
Recruiting
Phase 4

ASPIrin in Reducing Events in Dialysis ( ASPIRED )

CKD (Chronic Kidney Disease) Stage 5D
Guangdong Provincial People's Hospital9,000 enrolled139 locationsNCT04381143
Recruiting
Phase 4

ACE Reno, Pico Cell Matrix and Its Effect on eGFR in Chronic Kidney Diseases

Chronic Kidney DiseaseDiabetic NephropathiesChronic Kidney Disease (Stages 4 and 5)+5 more
Ace Cells Lab Limited300 enrolled1 locationNCT07187713
Recruiting
Phase 4

Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)

Esophageal CancerGastric CancerGastrointestinal Cancer+1 more
Cedars-Sinai Medical Center15 enrolled1 locationNCT07124351
Recruiting
Phase 4

Stellate Ganglion Block

LobectomyEsophagectomyPneumonectomy
University of Minnesota48 enrolled1 locationNCT06271707
Recruiting
Phase 4

Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan

Extensive-stage Small-cell Lung Cancer
Pharmacosmos A/S302 enrolled1 locationNCT05874401
Recruiting
Phase 4

Non-antithrombotic Versus. Single Antiplatelet Therapy Following Left Atrial Appendage Closure

Left Atrial Appendage ClosureAspirinNonvalvular Atrial Fibrillation+2 more
OCEAN-SHD Study Group500 enrolled21 locationsNCT07125417
Recruiting
Phase 4

Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity

ObesityWeight LossWeight Management+2 more
The Royal's Institute of Mental Health Research40 enrolled3 locationsNCT06809166
Recruiting
Phase 4

Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer

Esophageal AdenocarcinomaGastric AdenocarcinomaStage IIB Gastric Cancer+6 more
University of Chicago36 enrolled3 locationsNCT02366819
Recruiting
Phase 4

Vaccine Immunity and Inflammation in the Aging Person Living With HIV

AgeHIV Infections
Hennepin Healthcare Research Institute250 enrolled1 locationNCT06514547
Recruiting
Phase 4

"Extended" (Alternate Day) Antipsychotic Dosing

Drug TherapySchizophrenia and Related DisordersAntipsychotic Agents+1 more
Centre for Addiction and Mental Health120 enrolled1 locationNCT04478838
Recruiting
Phase 4

Randomised Evaluation of Sodium Dialysate Levels on Vascular Events

End-stage Kidney Disease
University of Sydney50,000 enrolled264 locationsNCT02823821
Recruiting
Phase 4

Chemoradiotherapy With Surgery Followed by Consolidation Durvalumab

Non-Small Cell Lung Cancer (Stage III)
Idris Bahce38 enrolled1 locationNCT06908070