Psilocybin Clinical Trials

58 recruitingDrug
Phase 231Phase 121Early Phase 16Phase 32Not Applicable2

Showing 120 of 58 trials

Recruiting
Phase 1

The RECAP2 Study: Midazolam and Psilocybin

Psilocybin
University of Wisconsin, Madison60 enrolled1 locationNCT06692192
Recruiting
Phase 1

The ENHANCE Study: taVNS and Psilocybin

HealthyVagus Nerve StimulationPsychedelic Experiences
University of Wisconsin, Madison108 enrolled1 locationNCT05866471
Recruiting
Phase 2

Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer

Lung Non-Small Cell CarcinomaUnipolar Depression
Alan Davis10 enrolled1 locationNCT07216404
Recruiting
Phase 2

A Randomized Neuroimaging Trial of Psilocybin in Depression

Depressive DisorderMajor Depressive Disorder
Sunnybrook Health Sciences Centre50 enrolled1 locationNCT06072898
Recruiting
Phase 1

Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD

Obsessive-Compulsive Disorder
Centre for Addiction and Mental Health10 enrolled1 locationNCT06299319
Recruiting
Phase 2

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

Hematopoietic and Lymphatic System NeoplasmMetastatic Malignant Solid NeoplasmDepression+1 more
University of Washington18 enrolled1 locationNCT07336238
Recruiting
Phase 1

Psilocybin for Treatment-Resistant Depression in Autism

Autism Spectrum DisorderTreatment Resistant Depression
Centre for Addiction and Mental Health20 enrolled1 locationNCT06731621
Recruiting
Phase 1

Psilocybin-assisted Treatment for Cannabis Use Disorder

Cannabis Use Disorder
Johns Hopkins University12 enrolled1 locationNCT06660381
Recruiting
Early Phase 1

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

DepressionDepressive SymptomsAlzheimer Disease+1 more
Johns Hopkins University20 enrolled1 locationNCT04123314
Recruiting
Phase 1

Open-Label Psilocybin Study in Transdiagnostic Population

AnxietyDepression - Major Depressive DisorderPTSD+5 more
Yale University50 enrolled1 locationNCT06442423
Recruiting
Early Phase 1

Psilocybin-facilitated Treatment for Chronic Pain

Fibromyalgia, Primary
University of Alabama at Birmingham30 enrolled1 locationNCT05068791
Recruiting
Phase 2

Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa

Anorexia Nervosa
Region Skane40 enrolled1 locationNCT07169747
Recruiting
Phase 2

Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy

Advanced CancerDepression, AnxietyPsilocybin-Assisted Psychotherapy
M.D. Anderson Cancer Center30 enrolled1 locationNCT06200155
Recruiting
Phase 2

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

CancerDepressionAnxiety
M.D. Anderson Cancer Center20 enrolled1 locationNCT06801041
Recruiting
Phase 2

Study of Psilocybin for Anorexia in Young Adults

Anorexia Nervosa
Marissa Raymond-Flesch, MD, MPH40 enrolled2 locationsNCT06399263
Recruiting
Phase 1Phase 2

Effects of Psilocybin on Electrophysiology and the Dynamic Content of Thought

Healthy
Johns Hopkins University30 enrolled1 locationNCT05301608
Recruiting
Phase 1

Investigation of Psychedelic Effects in Psychoactive Substances

Psychedelic Effects in Healthy Volunteers
Johns Hopkins University50 enrolled1 locationNCT06772753
Recruiting
Phase 3

Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)

Psychological Distress
Bruyère Health Research Institute.120 enrolled7 locationsNCT07063862
Recruiting
Early Phase 1

Safety Profile of Psilocybin for Cocaine Use Disorder

Cocaine Use Disorder
University of California, Los Angeles10 enrolled1 locationNCT06102434
Recruiting
Phase 2

Psilocybin for Opioid Use Disorder (OUD)

NYU Langone Health480 enrolled5 locationsNCT06796062