Psilocybin Clinical Trials

63 recruitingDrug
Phase 233Phase 122Early Phase 17Phase 33Not Applicable2

Showing 120 of 63 trials

Recruiting
Phase 1

Psilocybin in Chronic Low Back Pain and Depression

DepressionChronic Low-back Pain
Johns Hopkins University40 enrolled1 locationNCT06355414
Recruiting
Phase 2

Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

Opioid-use Disorder
Johns Hopkins University90 enrolled1 locationNCT06067737
Recruiting
Phase 3

The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder

Major Depressive Disorder
Sharmin Ghaznavi20 enrolled1 locationNCT06247839
Recruiting
Phase 3

Effect of Psilocybin and Structured Integrated Reframing Therapy on Gut-Brain Axis Biomarkers and Depression in Major Depressive Disorder

Post Traumatic Stress Disorder (PTSD)Major Depressive Disorder
Khyber Medical University Peshawar60 enrolled3 locationsNCT07703722
Recruiting
Early Phase 1

Mechanistic Studies of Psilocybin in Headache Disorders

Migraine
Yale University50 enrolled1 locationNCT06464367
Recruiting
Phase 3

Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)

Psychological Distress
Bruyère Health Research Institute.120 enrolled7 locationsNCT07063862
Recruiting
Phase 1

Investigating the Mechanisms of the Effects of Psilocybin on Visual Perception and Visual Representations in the Brain

Perception Disorders
University of California, Berkeley80 enrolled1 locationNCT05265546
Recruiting
Phase 2

Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD

Alcohol Use Disorder
NYU Langone Health200 enrolled1 locationNCT06349083
Recruiting
Phase 1

Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)

Opioid-use Disorder
Yale University12 enrolled1 locationNCT06160284
Recruiting
Phase 2

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

Tobacco Use Disorder
Johns Hopkins University66 enrolled3 locationsNCT05452772
Recruiting
Phase 2

Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy

Advanced CancerDepression, AnxietyPsilocybin-Assisted Psychotherapy
M.D. Anderson Cancer Center30 enrolled1 locationNCT06200155
Recruiting
Phase 2

Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD

Post Traumatic Stress DisorderPTSDChronic PTSD
Unity Health Toronto15 enrolled1 locationNCT06386003
Recruiting
Phase 2

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

CancerDepressionAnxiety
M.D. Anderson Cancer Center20 enrolled1 locationNCT06801041
Recruiting
Early Phase 1

Psilocybin Administration With 5-HT1a Blockade

Psychedelic Effects in Healthy Volunteers
Johns Hopkins University18 enrolled1 locationNCT07565493
Recruiting
Phase 2

Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers of Patients With Advanced Cancer

Caregiver Distress
University Health Network, Toronto15 enrolled1 locationNCT07048743
Recruiting
Phase 2

Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers

Healthy Participants With Lower-than-average Mental Well-being
Robin Carhart-Harris, PhD, MA120 enrolled1 locationNCT06626139
Recruiting
Phase 2

Psilocybin Therapy for Depression in Parkinson's Disease

DepressionParkinson Disease
Joshua Woolley, MD, PhD60 enrolled1 locationNCT06455293
Recruiting
Phase 2

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

Hematopoietic and Lymphatic System NeoplasmMetastatic Malignant Solid NeoplasmDepression+1 more
University of Washington18 enrolled1 locationNCT07336238
Recruiting
Phase 1

Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder

PTSD
University of New Mexico36 enrolled1 locationNCT07506395
Recruiting
Phase 2

Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer

Lung Non-Small Cell CarcinomaUnipolar Depression
Alan Davis10 enrolled1 locationNCT07216404