Phase 3 AML Clinical Trials
17 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–17 of 17 trials
Recruiting
Phase 2Phase 3
L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML
Acute Myeloid Leukaemia (AML)
Moleculin Biotech, Inc.312 enrolled25 locationsNCT06788756
Recruiting
Phase 3
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
Acute Myeloid Leukemia (AML)
Kura Oncology, Inc.1,300 enrolled39 locationsNCT07007312
Recruiting
Phase 3
Standard-dose vs Intermediate-dose Cytarabine Induction in the Treatment of Acute Myeloid Leukemia With RUNX1-RUNX1T1
AMLRUNX1-RUNX1T1 Fusion Protein Expression
Institute of Hematology & Blood Diseases Hospital, China300 enrolled1 locationNCT06744504
Recruiting
Phase 3
MRD-guided Maintenance Post-HCT: Gilteritini vs Sorafenib
Acute Myeloid Leukemia (AML)Maintenance TherapyAllogeneic Hematopoietic Cell Transplantation (HCT)+3 more
The First Affiliated Hospital of Soochow University594 enrolled2 locationsNCT07463651
Recruiting
Phase 3
Comparison of VA and D/IA Induction Regimens in Elderly Fit Acute Myeloid Leukemia Patients
AML, Adult
Institute of Hematology & Blood Diseases Hospital, China240 enrolled1 locationNCT07132684
Recruiting
Phase 3
The Efficacy of Therapy in Patients With Acute Myeloid Leukemia and Down Syndrome in Russia
AML (Acute Myelogenous Leukemia)Down Syndrome (DS)
Federal Research Institute of Pediatric Hematology, Oncology and Immunology100 enrolled1 locationNCT07232134
Recruiting
Phase 3
Effectiveness of Medium-Dose Cytarabine Combined With Venetoclax for Consolidation Therapy in Elderly Patients With Intermediate to High-Risk Acute Myeloid Leukemia
ElderlyAcute Myeloid Leukemia (AML)
Yehui Tan68 enrolled1 locationNCT06990321
Recruiting
Phase 2Phase 3
Molecular Genetics Guide the Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation
AMLMDS
Ruijin Hospital126 enrolled1 locationNCT06972641
Recruiting
Phase 3
An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy.
Acute Myeloid Leukemia (AML)
Servier Affaires Médicales245 enrolled15 locationsNCT05907057
Recruiting
Phase 3
Comparing Post-Transplant Cyclophosphamide As GVHD Prophylaxis to Standard of Care for Acute Leukemia Patients
Acute Myeloid Leukemia (AML) in RemissionAcute Lymphoblastic Leukemia (ALL) in Complete Remission
King Faisal Specialist Hospital & Research Center264 enrolled1 locationNCT04314219
Recruiting
Phase 3
Studying Conditioning Regimen In Pediatric Transplantation - AML , SCRIPT-AML
Acute Myeloid Leukemia (AML) in RemissionStem Cell Transplantation
Vastra Gotaland Region170 enrolled17 locationsNCT05477589
Recruiting
Phase 2Phase 3
Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR
Acute Myeloid Leukemia (AML)
University Hospital, Angers3,100 enrolled56 locationsNCT02416388
Recruiting
Phase 2Phase 3
Innate Donor Effector Allogeneic Lymphocyte Infusion After Stem Cell Transplantation: the IDEAL Trial
AML/MDS
Rigshospitalet, Denmark80 enrolled1 locationNCT05686538
Recruiting
Phase 2Phase 3
Treateament of Newly Diagnosed Acute Monocytic Leukemia in Children
Pediatric AMLLeukemia, Monocytic, Acute
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University43 enrolled9 locationsNCT05313958
Recruiting
Phase 2Phase 3
AZA + Venetoclax as Maintenance Therapy in Younger Adults With AML in First Remission
Acute Myeloid Leukemia (AML) in Remission
The First Affiliated Hospital of Soochow University124 enrolled2 locationsNCT05404906
Recruiting
Phase 3
A Randomised Phase III Study of Elacytarabine vs. Investigator’s Choice in Patients with Late Stage Acute Myeloid Leukaemia
Relapsed / refractory AML
Clavis Pharma ASA350 enrolled12 locationsACTRN12611000474954
Recruiting
Phase 3
Randomized Study Comparing Intravenous Busulfan (i.v. Bu; Busilvex [Registered Trademark]) plus Fludarabine (Buflu) Versus Intravenous Busulfan Plus Cyclophosphamide (Bucy2) As Conditioning Regimens Prior To Allogeneic Hematopoietic Stem Cell Transplantation (ALLOHSCT) In Patients (from 40 to 55 years) With Acute Myeloid Leukemia (AML) In Complete Remission (CR).
Acute Myeloid Leukemia (AML)
GITMO (Gruppo Italiano Trapianto Midollo Osseo)240 enrolled1 locationACTRN12609000997257