Amyloid Clinical Trials in Boston, Massachusetts
24 recruitingBoston, Massachusetts
Showing 1–20 of 24 trials
Recruiting
Phase 3
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals1,250 enrolled233 locationsNCT07052903
Recruiting
Phase 2
A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy
Cerebral Amyloid Angiopathy
Alnylam Pharmaceuticals200 enrolled57 locationsNCT06393712
Recruiting
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
Cardiac AmyloidosisCardiomyopathy, HypertrophicLumbar Spinal Stenosis+3 more
Columbia University1,663 enrolled6 locationsNCT06034405
Recruiting
Phase 1Phase 2
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
Alzheimer s DiseaseBeta-AmyloidProdromal Alzheimer's Disease+2 more
AC Immune SA304 enrolled26 locationsNCT05462106
Recruiting
ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)
Transthyretin-Mediated AmyloidosisATTR Amyloidosis
Alnylam Pharmaceuticals1,500 enrolled40 locationsNCT04561518
Recruiting
Phase 3
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S1,280 enrolled290 locationsNCT07207811
Recruiting
Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
Transthyretin AmyloidosisATTR-CMATTRv-PN+3 more
AstraZeneca1,850 enrolled67 locationsNCT06465810
Recruiting
Phase 1Phase 2
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion
Immunoglobulin Light Chain (AL) Amyloidosis
AbbVie76 enrolled23 locationsNCT06158854
Recruiting
Phase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company587 enrolled101 locationsNCT06563895
Recruiting
Phase 3
Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis
AL Amyloidosis
SWOG Cancer Research Network338 enrolled117 locationsNCT06022939
Recruiting
Phase 1Phase 2
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
AmyloidosisLight Chain AmyloidosisRelapsed AL Amyloidosis+1 more
Alexion Pharmaceuticals, Inc.91 enrolled18 locationsNCT07081646
Recruiting
Phase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics1,200 enrolled132 locationsNCT06128629
Recruiting
Phase 1Phase 2
Elranatamab in Patients With Relapsed or Refractory AL Amyloidosis
AL Amyloidosis
Brigham and Women's Hospital49 enrolled1 locationNCT06569147
Recruiting
Not Applicable
Molecular Imaging of Primary Amyloid Cardiomyopathy
CardiomyopathyAmyloidosis, Primary
Brigham and Women's Hospital171 enrolled1 locationNCT02641145
Recruiting
Phase 4
Ultrasound Therapy In Cardiac Amyloidosis
Amyloidosis Cardiac
Brigham and Women's Hospital70 enrolled1 locationNCT04667494
Recruiting
US Benchmarking Clinical Study
Cardiac AmyloidosisHFpEF - Heart Failure With Preserved Ejection FractionHFmrEF+2 more
eMyosound SAS150 enrolled3 locationsNCT07215715
Recruiting
Phase 1Phase 2
Study of NXC-201 CAR-T in Patients With Light Chain (AL) Amyloidosis
Light Chain (AL) Amyloidosis
Nexcella Inc.40 enrolled18 locationsNCT06097832
Recruiting
Phase 1Phase 2
Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis
AL Amyloidosis
Rajshekhar Chakraborty, MD53 enrolled4 locationsNCT05451771
Recruiting
Not Applicable
Exercise Training in Transthyretin Cardiac Amyloidosis
Amyloid CardiomyopathyTransthyretin Cardiac Amyloidosis
Brigham and Women's Hospital40 enrolled1 locationNCT05797857
Recruiting
Not Applicable
Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF
Heart FailureAmyloidosisHeart Failure, Diastolic+1 more
Massachusetts General Hospital515 enrolled1 locationNCT05577819