Phase 2 Anemia Clinical Trials
65 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 65 trials
Recruiting
Phase 2
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells
MDS (Myelodysplastic Syndrome)Severe Aplastic Anemia
National Heart, Lung, and Blood Institute (NHLBI)120 enrolled2 locationsNCT01174108
Recruiting
Phase 2
Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis
Paroxysmal Nocturnal Hemoglobinuria, PNHSevere Aplastic Anemia (SAA)Hypo-Plastic Myelodysplastic Syndrome (MDS)
National Heart, Lung, and Blood Institute (NHLBI)56 enrolled1 locationNCT03520647
Recruiting
Phase 1Phase 2
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome
Myelodysplastic Syndrome (MDS)Severe Aplastic AnemiaHypo-Plastic MDS
National Heart, Lung, and Blood Institute (NHLBI)37 enrolled1 locationNCT03173937
Recruiting
Phase 1Phase 2
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Healthy VolunteersAnemia, Sickle Cell
Bristol-Myers Squibb184 enrolled34 locationsNCT06481306
Recruiting
Phase 2
Study of Ianalumab in Adults With Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) Who Have Previously Benefited From Ianalumab
Warm Autoimmune Hemolytic AnemiaPrimary immune thrombocytopenia
Novartis Pharmaceuticals60 enrolled22 locationsNCT07039422
Recruiting
Phase 2
MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.
Severe Aplastic AnemiaAcquired Amegakaryocytic ThrombocytopeniaAcquired Pure Red Cell Aplasia+1 more
Masonic Cancer Center, University of Minnesota60 enrolled1 locationNCT06412497
Recruiting
Phase 1Phase 2
Afatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC)
Head and Neck Squamous Cell CarcinomaFanconi Anemia
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau25 enrolled2 locationsNCT06648096
Recruiting
Phase 2
Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm Infants
Iron-Deficiency AnemiaIron-deficiencyPrematurity+1 more
University of Washington120 enrolled1 locationNCT05340465
Recruiting
Phase 2
Iron Replacement to Reduce Anemia During Neoadjuvant Chemotherapy
Anemia
Fox Chase Cancer Center34 enrolled1 locationNCT05800600
Recruiting
Phase 2
Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin
AlbuminuriaSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)
University of Illinois at Chicago20 enrolled1 locationNCT07175051
Recruiting
Phase 1Phase 2
JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure
Severe Aplastic AnemiaSingle Lineage Cytopenias, T-LGLHypoplastic MDS
National Heart, Lung, and Blood Institute (NHLBI)145 enrolled1 locationNCT05998408
Recruiting
Phase 1Phase 2
Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia
Myelodysplastic SyndromesMyelofibrosisAnemia+4 more
Disc Medicine, Inc150 enrolled25 locationsNCT05320198
Recruiting
Phase 2
Study of DISC-0974-201 in Participants With IBD and Anemia
AnemiaInflammatory Bowel Disease (IBD)Inflammatory Bowel Disease (IBD); Anemia
Disc Medicine, Inc21 enrolled9 locationsNCT07368972
Recruiting
Phase 1Phase 2
Treating Anemia in Myelofibrosis With Repurposed Drugs (Nelfinavir) That Restore Iron Delivery to the Bone Marrow
MyelofibrosisMyelofibrosis; Anemia
University of California, Irvine10 enrolled1 locationNCT07281781
Recruiting
Phase 2
Indication of HSCT in Patients With Refractory/Relapse AA After First-line Standard Immunosuppressive Therapy Aged More Than 40 Years
Aplastic Anemia
Assistance Publique - Hôpitaux de Paris52 enrolled26 locationsNCT06646497
Recruiting
Phase 2
Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia
Severe Aplastic Anemia
Northside Hospital, Inc.20 enrolled2 locationsNCT02828592
Recruiting
Phase 1Phase 2
Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT
LeukemiaInborn Errors of MetabolismHLH+11 more
Children's Hospital of Philadelphia100 enrolled1 locationNCT06839456
Recruiting
Phase 2
Romiplostim Versus rhTPO for Platelet Engraftment After Transplant in MDS and AA
MDS (Myelodysplastic Syndrome)Aplastic Anemia (AA)
The First Affiliated Hospital of Soochow University66 enrolled1 locationNCT07400341
Recruiting
Phase 2
Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome
Myelodysplastic SyndromeAplastic Anemiade Novo Myelodysplastic Syndrome+1 more
M.D. Anderson Cancer Center140 enrolled1 locationNCT01624805
Recruiting
Phase 2
Alendronate for Osteonecrosis in Adults With Sickle Cell Disease
Sickle Cell DiseaseOsteonecrosisAvascular Necrosis+2 more
University of California, Davis30 enrolled1 locationNCT06016634