Phase 3 Arthritis Clinical Trials

87 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 87 trials

Recruiting
Phase 3

A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.

Osteoarthritis, Knee
Paradigm Biopharmaceuticals Ltd.466 enrolled52 locationsNCT06917404
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients

Knee Osteoarthritis
Doron Therapeutics Inc.260 enrolled17 locationsNCT07219771
Recruiting
Phase 3

Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

Arthritis, Psoriatic
MoonLake Immunotherapeutics AG600 enrolled135 locationsNCT06641089
Recruiting
Phase 3

A Study to Evaluate the Effect of Bimekizumab on Gene Expression Biomarkers in Study Participants With Moderate to Severe Plaque Psoriasis

Psoriatic ArthritisModerate to Severe Plaque Psoriasis
UCB Biopharma SRL90 enrolled16 locationsNCT06506916
Recruiting
Phase 3

OLE Study With Filgotinib in JIA

Juvenile Idiopathic Arthritis (JIA)
Alfasigma S.p.A.80 enrolled4 locationsNCT07553182
Recruiting
Phase 3

Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis

Active Juvenile Psoriatic Arthritis
Amgen60 enrolled45 locationsNCT04804553
Recruiting
Phase 3

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

OsteoarthritisOverweight or Obesity
Eli Lilly and Company900 enrolled154 locationsNCT07353931
Recruiting
Phase 3

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

Osteoarthritis
Eli Lilly and Company800 enrolled95 locationsNCT07153471
Recruiting
Phase 3

Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis

Polyarticular Course Juvenile Idiopathic Arthritis (JIA)
Duke University400 enrolled6 locationsNCT06654882
Recruiting
Phase 3

A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165) in Pediatric Participants With Juvenile Psoriatic Arthritis

Juvenile Psoriatic Arthritis
Bristol-Myers Squibb60 enrolled47 locationsNCT06869551
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced Participants With Active Psoriatic Arthritis

Arthritis, Psoriatic
Janssen Research & Development, LLC750 enrolled214 locationsNCT06807424
Recruiting
Phase 3

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines

Psoriatic Arthritis
Takeda1,088 enrolled189 locationsNCT06671483
Recruiting
Phase 3

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

Psoriatic Arthritis
Takeda600 enrolled122 locationsNCT06671496
Recruiting
Phase 2Phase 3

Efficacy of Two Ultrasound-guided Intra-articular Injections of Botox® Combined With Custom-made Rigid Splinting in Painful Base-of-thumb Osteoarthritis.

OsteoarthritisBase-of-thumb Osteoarthritis
Assistance Publique - Hôpitaux de Paris120 enrolled1 locationNCT06902805
Recruiting
Phase 3

Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain

Osteoarthritis Knee Pain
Saol Therapeutics Inc150 enrolled18 locationsNCT07226258
Recruiting
Phase 2Phase 3

A Study of Picankibart in Patients With Active Psoriatic Arthritis

Psoriatic Arthritis
Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.222 enrolled1 locationNCT07295509
Recruiting
Phase 3

Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis

Psoriatic Arthritis
Takeda1,182 enrolled1 locationNCT07286058
Recruiting
Phase 3

Metformin Safety and Efficacy in Osteoarthritis.

Osteo Arthritis Knee
Mostafa Bahaa70 enrolled1 locationNCT06231758
Recruiting
Phase 2Phase 3

Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

Joint PainArthritisGout+4 more
Olatec Therapeutics LLC300 enrolled40 locationsNCT05658575
Recruiting
Phase 3

NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis

Thumb Osteoarthritis
Mayo Clinic240 enrolled1 locationNCT05992883