Phase 3 Arthritis Clinical Trials
97 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 97 trials
Recruiting
Phase 3
Safety, Tolerability, Pharmacokinetics, and Efficacy of Filgotinib for the Treatment of Polyarticular-course Juvenile Idiopathic Arthritis in Children and Adolescents
Polyarticular Course Juvenile Idiopathic Arthritis
Alfasigma S.p.A.65 enrolled14 locationsNCT07554495
Recruiting
Phase 3
Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response
Arthritis, Psoriatic
MoonLake Immunotherapeutics AG600 enrolled138 locationsNCT06641089
Recruiting
Phase 3
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
Colitis UlcerativeArthritis, PsoriaticCrohns Disease+1 more
Janssen Research & Development, LLC196 enrolled47 locationsNCT06663332
Recruiting
Phase 3
A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165) in Pediatric Participants With Juvenile Psoriatic Arthritis
Juvenile Psoriatic Arthritis
Bristol-Myers Squibb60 enrolled47 locationsNCT06869551
Recruiting
Phase 2Phase 3
Cannabidiol (CBD) in Pain Reduction for Knee Osteoarthritis
Knee arthritis
NYU Langone Health100 enrolled1 locationNCT05020028
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis
Arthritis, Psoriatic
Janssen Research & Development, LLC750 enrolled216 locationsNCT06807424
Recruiting
Phase 3
An Open-label Study to Evaluate the Pharmacokinetics and Safety of Bimekizumab in Pediatric Study Participants With Active Juvenile Idiopathic Arthritis Subtypes Enthesitis-related Arthritis (Including Juvenile-onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis
Enthesitis Related ArthritisJuvenile Psoriatic Arthritis
UCB Biopharma SRL40 enrolled23 locationsNCT06668181
Recruiting
Phase 3
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
OsteoarthritisOverweight or Obesity
Eli Lilly and Company900 enrolled160 locationsNCT07353931
Recruiting
Phase 3
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee
Osteoarthritis
Eli Lilly and Company800 enrolled95 locationsNCT07153471
Recruiting
Phase 3
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
ObesityKnee osteoarthritis (OA)
Novo Nordisk A/S400 enrolled82 locationsNCT07481630
Recruiting
Phase 3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
ObesityOverweightOsteoarthritis, Knee
Novo Nordisk A/S400 enrolled81 locationsNCT07509307
Recruiting
Phase 3
Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis
Polyarticular Course Juvenile Idiopathic Arthritis (JIA)
Duke University400 enrolled6 locationsNCT06654882
Recruiting
Phase 3
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines
Psoriatic Arthritis
Takeda1,088 enrolled189 locationsNCT06671483
Recruiting
Phase 3
Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.
Juvenile Idiopathic Arthritis
AbbVie90 enrolled56 locationsNCT05609630
Recruiting
Phase 3
A Long-term Extension Clinical Study of TLL-018 in Patients With Rheumatoid Arthritis
Rheumatoid Arthritis
Hangzhou Highlightll Pharmaceutical Co., Ltd350 enrolled1 locationNCT06887127
Recruiting
Phase 3
A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis
Juvenile Idiopathic Arthritis
Eli Lilly and Company190 enrolled80 locationsNCT03773965
Recruiting
Phase 3
A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab
Juvenile Psoriatic Arthritis
AbbVie40 enrolled32 locationsNCT06100744
Recruiting
Phase 3
Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain
Osteoarthritis Knee Pain
Saol Therapeutics Inc150 enrolled20 locationsNCT07226258
Recruiting
Phase 3
A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.
Osteoarthritis, Knee
Paradigm Biopharmaceuticals Ltd.466 enrolled56 locationsNCT06917404
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients
Knee Osteoarthritis
Doron Therapeutics Inc.260 enrolled17 locationsNCT07219771