Phase 2 Arthritis Clinical Trials
138 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 138 trials
Recruiting
Phase 2
A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)
Juvenile Idiopathic Arthritis
Sanofi51 enrolled31 locationsNCT02991469
Recruiting
Phase 2
A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)
Arthritis, Rheumatoid
Merck Sharp & Dohme LLC182 enrolled62 locationsNCT07176390
Recruiting
Phase 2
Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)
Psoriatic Arthritis
Merck Sharp & Dohme LLC140 enrolled4 locationsNCT07486960
Recruiting
Phase 2
A Phase II Study to Evaluate the Efficacy and Safety of D-2570 in Subjects With Active Psoriatic Arthritis
PsA (Psoriatic Arthritis)
InventisBio Co., Ltd222 enrolled1 locationNCT07315061
Recruiting
Phase 2
A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)
Active Rheumatoid Arthritis
Elevara Medicines Limited180 enrolled29 locationsNCT07409103
Recruiting
Phase 2
A Study of SPY072 in Rheumatic Disease
Rheumatoid ArthritisPsoriatic ArthritisRheumatic Diseases+5 more
Spyre Therapeutics, Inc.285 enrolled57 locationsNCT07148414
Recruiting
Phase 2
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Osteoarthritis, Knee
Eli Lilly and Company10,000 enrolled64 locationsNCT05986292
Recruiting
Phase 2
Phase II Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis
Knee Osteoarthritis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology100 enrolled3 locationsNCT07547735
Recruiting
Phase 2
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
Radiographic Axial Spondyloarthritis
Merck Sharp & Dohme LLC315 enrolled95 locationsNCT07133633
Recruiting
Phase 1Phase 2
CBD for Pain Following Orthopedic Shoulder Surgery
Shoulder Osteoarthritis
The Methodist Hospital Research Institute80 enrolled1 locationNCT06381791
Recruiting
Phase 1Phase 2
EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial - 1)
Axial Spondyloarthritis (AxSpA)
Grey Wolf Therapeutics141 enrolled14 locationsNCT07047703
Recruiting
Phase 2
Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty
Knee Replacement SurgeryOsteoarthritis, Knee
Chad Brummett380 enrolled2 locationsNCT06234631
Recruiting
Phase 1Phase 2
Controlling Hyperactive Immunity With Long-lived Lymphocytes
Rheumatoid Arthritis (RA)Autoimmune Rheumatologic DiseaseDiffuse Cutaneous Systemic Sclerosis+1 more
Quell Therapeutics Limited16 enrolled6 locationsNCT07473154
Recruiting
Phase 2
A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis
Knee OsteoarthritisSynovitis of Knee
4Moving Biotech129 enrolled22 locationsNCT07225829
Recruiting
Phase 2
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
Rheumatoid Arthritis
AbbVie180 enrolled70 locationsNCT06972446
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis
Arthritis, Psoriatic
Janssen Research & Development, LLC240 enrolled40 locationsNCT07321873
Recruiting
Phase 2
A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)
Rheumatoid Arthritis
Hoffmann-La Roche160 enrolled32 locationsNCT07137598
Recruiting
Phase 2
A Study to Evaluate the Efficacy,Safety,Tolerability,Pharmacokinetics,and Immunogenicty of Plonmarlimab in Subjects With Acute Gouty Arthritis
Acute Gouty Arthritis
TJ Biopharma Co., Ltd.170 enrolled1 locationNCT07453004
Recruiting
Phase 2
A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
Progressive Pulmonary FibrosisInterstitial Lung DiseasePulmonary Fibrosis+4 more
Avalyn Pharma Inc.375 enrolled152 locationsNCT06329401
Recruiting
Phase 2
Pharmacokinetics, Efficacy and Safety of Olokizumab In Patients With Juvenile Idiopathic Arthritis
Juvenile Idiopathic Arthritis
R-Pharm International, LLC71 enrolled14 locationsNCT07517575