Phase 1 Blood Clinical Trials
28 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 28 trials
Recruiting
Phase 1
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies
Leukemia, Lymphocytic, AcuteBlood CancerMyeloid Leukemia, Acute+8 more
National Cancer Institute (NCI)86 enrolled1 locationNCT06904066
Recruiting
Phase 1Phase 2
Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
Hypoxia, BrainBlood PressureStroke+5 more
University of Calgary12 enrolled1 locationNCT03255408
Recruiting
Phase 1Phase 2
The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation
Hematopoietic Stem Cell TransplantationPeripheral Blood Stem Cell Transplantation
National Cancer Institute (NCI)260 enrolled2 locationsNCT05436418
Recruiting
Phase 1
Comparative Analysis of Biotinylated, Irradiated and 51-Chromium Radiolabeled Red Blood Cells for Analysis of Recovery and Survival After Autologous Transfusion
Healthy Volunteer Red Blood Cell Labeling Study; Not Disease Focused
Jose Cancelas20 enrolled2 locationsNCT07446647
Recruiting
Phase 1
Understanding the Health Effect of a Bioactive Peptide From Egg: A Pilot Study
High Blood SugarOverweight and ObesityHigh Blood Pressure
University of Alberta28 enrolled1 locationNCT06555393
Recruiting
Phase 1Phase 2
Application of [68Ga]Ga-NI-FAPI-04 PET/CT Imaging in Fibroblast Activation Protein Related Diseases
TumorCardiovascular DiseasesPulmonary Fibrosis+3 more
Peking Union Medical College Hospital30 enrolled1 locationNCT07464132
Recruiting
Phase 1Phase 2
A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax
LeukemiaBlood CancersBlood Cancer+1 more
Jacqueline Garcia, MD31 enrolled2 locationsNCT07148180
Recruiting
Phase 1Phase 2
Polypill for Prevention of Cardiomyopathy
Type 2 DiabetesHigh Blood Pressure
University of Texas Southwestern Medical Center200 enrolled1 locationNCT06143566
Recruiting
Phase 1
Mitigating the Pro-inflammatory Phenotype of Obesity
ObesityInsulin ResistanceBlood Pressure+3 more
University of Kansas Medical Center60 enrolled1 locationNCT04934228
Recruiting
Phase 1Phase 2
IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers
Multiple MyelomaNHLRefractory Non-Hodgkin Lymphoma+1 more
Indapta Therapeutics, INC.128 enrolled12 locationsNCT06119685
Recruiting
Phase 1
Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis
SurgeryPostoperative Blood Loss
Vanderbilt University Medical Center60 enrolled1 locationNCT05774717
Recruiting
Phase 1Phase 2
Effect of Dexmedetomidine on Hemodynamic Response to Endotracheal Intubation in Hypertensive Patients
Blood PressureElective Surgical PatientHypertensive Patients+2 more
Liaquat National Hospital & Medical College60 enrolled1 locationNCT06712186
Recruiting
Phase 1
Phenylephrine Tumescence for Hemostasis in Surgery for Burn Injury
Blood Loss, Surgical
University of Manitoba24 enrolled1 locationNCT01731444
Recruiting
Phase 1
A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study
NeoplasmsMultiple MyelomaCardiovascular Diseases+11 more
OriCell Therapeutics Co., Ltd.81 enrolled1 locationNCT06271252
Recruiting
Phase 1Phase 2
A Study to Investigate Safety and Clinical Activity of Belantamab Mafodotin in Combination With Lenalidomide, Dexamethasone and Nirogacestat in Patients With Transplant Ineligible Newly Diagnosed Multiple Myeloma
NeoplasmsMultiple MyelomaParaproteinemias+5 more
Hellenic Society of Hematology36 enrolled2 locationsNCT05573802
Recruiting
Phase 1
CAR T cell therapy for CD19-positive cancer - phase I clinical trial
B cell blood cancers, including non-Hodgkin's lymphoma and leukaemia.
Metro North Hospital and Health Service31 enrolled1 locationACTRN12621000762853
Completed
Phase 1
Is it safe to monitor non-invasive hemoglobin in major surgery?
blood transfusionhemoglobin concentration
Ayten saracoglu20 enrolled1 locationACTRN12619001468112
Completed
Phase 1
Infusion of virus specific immune cells in patients at the first sign of virus infection after a blood or bone marrow transplant who have received less than 7 days of anti-viral treatment.
Cytomegalovirus reactivation or infection following allogeneic blood or marrow stem cell transplantationAdenovirus reactivation or infection following allogeneic blood or marrow stem cell transplantationEpstein Barr Virus reactivation or infection following allogeneic blood or marrow stem cell transplantation
Western Sydney Local Health District31 enrolled3 locationsACTRN12618000343202
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of 600 mg imatinib tablet against the innovator imatinib tablet conducted under fed conditions in healthy male volunteers
Blood DisordersCancerLeukaemia
Zenith Technology Corp Ltd24 enrolled1 locationACTRN12617000740392
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of Inhaled Insulin against the innovators Humalog KwikPen for injection and the AFREZZA Inhalation Powder Cartridge conducted under fasting conditions in healthy male and female volunteers
Pharmacokinetic and pharmacodynamic study conducted in healthy volunteers comparing three formulations of Insulin with no health condition or problem studied.
Insulin is a medicine that is used to lower blood glucose.
Zenith Technology Corp Ltd18 enrolled1 locationACTRN12615001100583