Breast Cancer Stage II Clinical Trials

16 recruiting

Breast Cancer Stage II Trials at a Glance

19 actively recruiting trials for breast cancer stage ii are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Phase 2 with 9 trials, with the heaviest enrollment activity in New York, Houston, and Boston. Lead sponsors running breast cancer stage ii studies include Baylor Breast Care Center, Branch Office of "Hadassah Medical Ltd", and Barbara Ann Karmanos Cancer Institute.

Browse breast cancer stage ii trials by phase

Treatments under study

About Breast Cancer Stage II Clinical Trials

Looking for clinical trials for Breast Cancer Stage II? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Breast Cancer Stage II trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Breast Cancer Stage II clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting
Not Applicable

A Study of the TheraBionic P1 Device in Breast Cancer

HER2-negative Breast CancerBreast Cancer Stage IBreast Cancer Stage II+2 more
Barbara Ann Karmanos Cancer Institute24 enrolled8 locationsNCT07218432
Recruiting
Not Applicable

A Study of Language Interpretation Solutions for People With Breast Cancer

Breast CancerBreast Cancer Stage IIBreast Cancer Stage III
Memorial Sloan Kettering Cancer Center700 enrolled8 locationsNCT06721065
Recruiting
Not Applicable

Evaluation of the Efficacy of Biobran (Rice Bran Arabinoxylan) in Supporting Breast Cancer Chemotherapy

Breast Cancer Stage IIIBreast Cancer Stages IBreast Cancer Stages II
China Medical University Hospital96 enrolled2 locationsNCT07503496
Recruiting
Not Applicable

Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial

Breast Cancer Stage IBreast Cancer Stage IIBreast Cancer Stage III+4 more
Fred Hutchinson Cancer Center100 enrolled1 locationNCT06802172
Recruiting
Phase 2

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

Breast CancerBreast CarcinomaBreast Neoplasm+34 more
University of California, Davis86 enrolled1 locationNCT06268665
Recruiting
Phase 2

Predicting Response to Neoadjuvant Endocrine Therapy (Neo-PREDICT)

Breast Cancer Stage IBreast Cancer Stage IIBreast Cancer Stage III
George Washington University90 enrolled1 locationNCT06806930
Recruiting
Phase 2

Neoadjuvant, SBRT With Intratumoural Pembrolizumab Followed by Neoadjuvant Chemotherapy in Breast Cancer

Breast CancerBreast Cancer Stage IIBreast Cancer Invasive+2 more
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's40 enrolled2 locationsNCT07188246
Recruiting
Phase 1Phase 2

A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC

Metastatic Breast CancerBreast Cancer Stage IBreast Cancer Stage II+2 more
Forward Pharmaceuticals Co., Ltd.196 enrolled1 locationNCT07002177
Recruiting

A New Tool to Promote Patient's Engagement in Their Healthcare Process

Breast CarcinomaBreast Cancer Stage IBreast Cancer Stage II
European Institute of Oncology180 enrolled1 locationNCT06762496
Recruiting
Phase 2

TRUDI: TDXD+Durva in HER2+/Low IBC

Breast CancerInvasive Breast CancerHER2-positive Breast Cancer+2 more
Filipa Lynce, MD63 enrolled3 locationsNCT05795101
Recruiting
Not Applicable

Optimizing Surgical Decisions in Young Adults With Breast Cancer

Breast Cancer Stage IBreast Cancer Stage IIBreast Cancer Stage III+1 more
Weill Medical College of Cornell University800 enrolled4 locationsNCT06275126
Recruiting
Phase 2

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

Breast CancerBreast Cancer Stage IBreast Cancer Stage II+5 more
UNC Lineberger Comprehensive Cancer Center90 enrolled1 locationNCT06727773
Recruiting
Not Applicable

Radiotherapy Dose Adaptation Based on Tumor Biology in Patients With cN2b-N3 Breast Cancer

Breast Cancer Stage III
Samsung Medical Center120 enrolled1 locationNCT05896865
Recruiting

Evaluating and Monitoring Immune and Clinical Responses in Early-Stage Triple Negative Breast Cancer Undergoing Neoadjuvant Chemo-immunotherapy With Pembrolizumab

Breast Cancer Stage IIBreast Cancer InvasiveBreast Cancer Stage III+1 more
Emory University10 enrolled1 locationNCT05877859
Recruiting
Phase 2Phase 3

Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer

Breast CancerBreast Cancer Stage IBreast Cancer Stage II+1 more
University of Virginia45 enrolled1 locationNCT05288777
Recruiting
Not Applicable

Ways of Retaining the Inframammary Fold in Implant-based Breast Surgery

Breast Cancer Stage IBreast Cancer Stage IIIn Situ Breast Cancer
Branch Office of "Hadassah Medical Ltd"100 enrolled1 locationNCT06931548
Recruiting
Not Applicable

Evaluation of Radiobiological Effects in Skin Toxicities for Breast Cancer Patients With Pencil Beam Scanning Proton Therapy

Breast CancerBreast Cancer Stage IBreast Cancer Stage II+1 more
Covenant Health Cancer Center100 enrolled1 locationNCT06006806
Recruiting
Phase 2

Neoadjuvant and Adjuvant Ribociclib and ET for Clinically High-risk ER+ and HER2- Breast Cancer

Breast Cancer Stage II
SOLTI Breast Cancer Research Group1,100 enrolled51 locationsNCT05296746
Recruiting
Phase 2

Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer

Breast CancerBreast Cancer FemaleBreast Neoplasm+3 more
Baylor Breast Care Center185 enrolled2 locationsNCT05020860