Phase 1 CAR-T Cell Clinical Trials
10 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–10 of 10 trials
Recruiting
Phase 1Phase 2
CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus
CAR-T CellSLESystemic Lupus Erythematosus (SLE)+4 more
Children's Hospital of Philadelphia24 enrolled1 locationNCT06839976
Recruiting
Phase 1Phase 2
MB-CART2019.1 in Refractory Multiple Sclerosis
Multiple SclerosisCAR-T Cell Therapy
Miltenyi Biomedicine GmbH26 enrolled1 locationNCT07178431
Recruiting
Phase 1
A Study of A-CAR028 Treatment in Subjects With Relapsed or Refractory Acute Myeloid Leukemia
CAR-T Cell TherapyAcute Myeloid Leukemia (AML)
First Affiliated Hospital of Zhejiang University20 enrolled1 locationNCT07198867
Recruiting
Phase 1
Study of Therapeutic Efficacy of CAR-T Cell Therapy in Patients With MDR-SRNS
CAR-T Cell TherapyMulti-Drug Resistant Nephrotic Syndrome
The Children's Hospital of Zhejiang University School of Medicine18 enrolled1 locationNCT06553898
Recruiting
Phase 1
CD7 CAR T Cells (RD13-02) in the Treatment of Relapsed/Refractory Severe Aplastic Anemia
RelapseCAR-T Cell TherapyRefractory+1 more
Institute of Hematology & Blood Diseases Hospital, China15 enrolled1 locationNCT06622694
Recruiting
Phase 1
Study of Therapeutic Efficacy of Anti-CD19 CAR-T Cell Therapy in Patients With MDR-SRNS
CAR-T Cell TherapyMulti-Drug Resistant Nephrotic Syndrome
The Children's Hospital of Zhejiang University School of Medicine18 enrolled1 locationNCT06842589
Recruiting
Phase 1
Study of BCMA/CD70 CAR-T Therapy for Refractory cSLE
CAR-T Cell TherapySystemic Lupus ErythematosusBCMA
The Children's Hospital of Zhejiang University School of Medicine18 enrolled1 locationNCT06934447
Recruiting
Phase 1
GPC3/Mesothelin-CAR-γδT Cells Against Cancers
Liver CancerLung CancerPancreas Cancer+3 more
Second Affiliated Hospital of Guangzhou Medical University30 enrolled1 locationNCT06196294
Recruiting
Phase 1
Mesothelin/GPC3/GUCY2C-CAR-T Cells Against Cancers
Pancreas CancerSolid Tumor, AdultCAR-T Cell Therapy+1 more
Second Affiliated Hospital of Guangzhou Medical University30 enrolled1 locationNCT05779917
Recruiting
Phase 1
GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFβ/HER2/Lewis-Y/AXL/EGFR-CAR-T Cells Against Cancers
Lung CancerCancerImmunotherapy+1 more
Second Affiliated Hospital of Guangzhou Medical University30 enrolled2 locationsNCT03198052