Cardiovascular Clinical Trials in London

22 recruitingLondon, United Kingdom

Showing 120 of 22 trials

Recruiting
Phase 2Phase 3

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

Atherosclerotic Cardiovascular Disease
CSL Behring2,310 enrolled542 locationsNCT05485961
Recruiting
Phase 3

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1152 locationsNCT07064473
Recruiting
Phase 3

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

ObesityOverweightAtherosclerotic Cardiovascular Disease
Amgen12,800 enrolled759 locationsNCT07037433
Recruiting
Phase 3

Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

Atherosclerotic Cardiovascular Disease (ASCVD)Elevated Lp(a)
Eli Lilly and Company10,450 enrolled751 locationsNCT07157774
Recruiting
Phase 3

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

HypertensionHigh Risk Cardiovascular DiseaseHigh Cardiovascular Risk
Alnylam Pharmaceuticals11,000 enrolled597 locationsNCT07181109
Recruiting
Phase 3

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

Cardiovascular Disease
AstraZeneca15,100 enrolled1264 locationsNCT07000357
Recruiting

Product Surveillance Registry

Cardiac Rhythm DisordersNeurological DisordersCardiovascular Disorders+1 more
Medtronic100,000 enrolled391 locationsNCT01524276
Recruiting
Phase 1

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

HypercholesterolaemiaMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG90 enrolled18 locationsNCT07491172
Recruiting

The BRAVE Study- The Identification of Genetic Variants Associated With Bicuspid Aortic Valve Using a Combination of Case-control and Family-based Approaches.

Cardiovascular Diseases
University Hospitals, Leicester700 enrolled4 locationsNCT04514445
Recruiting
Not Applicable

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

Arterial Occlusive DiseasesCardiovascular DiseasesMyocardial Ischemia+4 more
Fundación EPIC700 enrolled13 locationsNCT07286578
Recruiting

Genetic Variants and Regulation of Specialized Pro-resolving Mediator

Cardiovascular DiseasesHealthyInflammatory Disease
Queen Mary University of London200 enrolled1 locationNCT04698291
Recruiting
Not Applicable

Artificial Intelligence Delivered Cardiac Magnetic Resonance - Prospective Validation

Cardiovascular DiseasesHealthy Volunteers
Imperial College London150 enrolled1 locationNCT06061822
Recruiting

Evaluation of the Clinical Benefit of the Aktiia Blood Pressure Monitoring for Early Awareness of Hypertension and Prediction of Cardiovascular Risk

HypertensionCardiovascular RiskBlood Pressure Check (Hypertension Screening)
Aktiia SA15,000 enrolled2 locationsNCT06670677
Recruiting
Not Applicable

Study on Optimal Temperature During Cardiopulmonary Bypass (THERMIC-4)

Cardiovascular DiseasesValvular Heart DiseaseIschemic Heart Disease
University of Leicester100 enrolled11 locationsNCT05996120
Recruiting

Inherited Cardiac cONditions In Kids

Cardiovascular DiseasesInherited Cardiac Conditions
Imperial College London300 enrolled3 locationsNCT05158738
Recruiting

The Oxford Risk Factors And Non-Invasive Imaging Study

Cardiovascular DiseasesCardiovascular Risk Factors
University of Oxford250,000 enrolled37 locationsNCT05169333
Recruiting

Adiposity, Cardiometabolic and Neurocognitive Health Among Ethnic Groups: a Feasibility and Pilot Study

ObesityCognitive ImpairmentCardiovascular Diseases+2 more
King's College Hospital NHS Trust10 enrolled2 locationsNCT06435611
Recruiting
Not Applicable

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates

Cardiovascular DiseasesEnd Stage Renal DiseaseKidney Transplantation+1 more
University of British Columbia3,306 enrolled22 locationsNCT03674307
Recruiting
Not Applicable

A Prospective Randomised Multi-centre Trial Comparing cArdiac MRI Guided CRT Versus Conventional CRT Implantation in Patients With Ischaemic Cardiomyopathy

Cardiovascular Diseases
Guy's and St Thomas' NHS Foundation Trust218 enrolled1 locationNCT03992560
Recruiting

The European NAFLD Registry

Hepatocellular CarcinomaObesityCardiovascular Diseases+9 more
Newcastle University10,000 enrolled37 locationsNCT04442334