Choroid Clinical Trials

32 recruitingLast updated: July 25, 2026

There are 32 actively recruiting choroid clinical trials across 28 countries. Studies span Phase 3, Not Applicable, Phase 1, Phase 2, Phase 4. Top locations include Paris, France, Nashville, Tennessee, United States, Barcelona, Spain. Updated daily from ClinicalTrials.gov.


Choroid Trials at a Glance

32 actively recruiting trials for choroid are listed on ClinicalTrialsFinder across 6 cities in 28 countries. The largest study group is Phase 3 with 6 trials, with the heaviest enrollment activity in Paris, Nashville, and Barcelona. Lead sponsors running choroid studies include Aura Biosciences, EyeBiotech Ltd., and Singapore National Eye Centre.

Browse choroid trials by phase

Treatments under study

About Choroid Clinical Trials

Looking for clinical trials for Choroid? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Choroid trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Choroid clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 32 trials

Recruiting
Phase 2Phase 3

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

Age-Related Macular DegenerationMacular DegenerationChoroidal Neovascularization+1 more
EyeBiotech Ltd.960 enrolled87 locationsNCT07440225
Recruiting
Phase 2Phase 3

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

Age-Related Macular DegenerationMacular DegenerationChoroidal Neovascularization+1 more
EyeBiotech Ltd.960 enrolled56 locationsNCT07496567
Recruiting
Phase 3

Safety and Efficacy Evaluation of SMZ1 With Ranibizumab in Patients With Neovascular Age-related Macular Degeneration Without Polypoidal Choroidal Vasculopathy

Neovascular (Wet) Age-related Macular Degeneration Without Polypoidal Choroidal Vasculopathy
SANGMYUNG innovation266 enrolled1 locationNCT07695207
Recruiting

Biomarkers and Choroidal Neovascularization

Mineralocorticoid ExcessChoroidal Neovascularization
Institut National de la Santé Et de la Recherche Médicale, France250 enrolled2 locationsNCT04439708
Recruiting

Familial Investigations of Childhood Cancer Predisposition

Pancreatic CancerHereditary Breast and Ovarian CancerHodgkin Lymphoma+43 more
St. Jude Children's Research Hospital1,500 enrolled1 locationNCT03050268
Recruiting

Progression Patterns of Choroidal Venous Alterations

Pachychoroid Disease
Singapore National Eye Centre250 enrolled4 locationsNCT07236671
Recruiting

Establishment of a Multimodal Standard Database for Inflammation-related Ophthalmopathy

Inflammatory DiseaseRetinal DiseaseOcular Surface Disease+1 more
Dan Chen3,000 enrolled1 locationNCT07628946
Recruiting

Inherited Retinal Degenerative Disease Registry

Retinitis PigmentosaBatten DiseaseLeber Congenital Amaurosis+25 more
Foundation Fighting Blindness20,000 enrolled1 locationNCT02435940
Recruiting

Choroidal and Retinal Features in PACD and POAG on OCT and OCTA

GlaucomaOCTAChoroid
Zhongshan Ophthalmic Center, Sun Yat-sen University132 enrolled1 locationNCT07580014
Recruiting

High Resolution Retinal Imaging

Geographic AtrophyAge-Related Macular DegenerationRetinitis Pigmentosa+2 more
University of Pennsylvania600 enrolled1 locationNCT01866371
Recruiting
Phase 1

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Germ Cell TumorChoroid Plexus CarcinomaCentral Nervous System Tumor+8 more
Seattle Children's Hospital90 enrolled1 locationNCT04185038
Recruiting
Phase 3

Efficacy and Durability of a Personalized Treat-and-extend Regimen of Faricimab for Treatment-naive Polypoidal Choroidal Vasculopathy

Age-Related Macular DegenerationPolypoidal Choroidal Vasculopathy (PCV)
Yeungnam University College of Medicine50 enrolled1 locationNCT07461441
Recruiting
Not Applicable

Choroid Plexus Dysfunction in Neurological Diseases

Metabolic SyndromePlexus Choroideus
Assistance Publique - Hôpitaux de Paris65 enrolled2 locationsNCT06403189
Recruiting
Phase 3

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

Uveal MelanomaChoroidal MelanomaIndeterminate Lesions+1 more
Aura Biosciences100 enrolled71 locationsNCT06007690
Recruiting

Choroidal Melanoma Patient-Reported Outcome Study (CM-PRO) in a Subset of AU-011-301 (CoMpass) Subjects

Uveal MelanomaChoroidal MelanomaIndeterminate Lesions+1 more
Aura Biosciences15 enrolled1 locationNCT07421739
Recruiting
Phase 4

Study to Investigate the Efficacy, Safety and Durability of Faricimab in Caucasian Patients With Polypoidal Choroidal Vasculopathy (MONDEGO)

Polypoidal Choroidal Vasculopathy
Association for Innovation and Biomedical Research on Light and Image120 enrolled31 locationsNCT06709339
Recruiting
Phase 3

Prospective Trial of the Efficacy and Safety of a Personalized Regimen of High-dose Aflibercept 8mg on Treatment-naive Polypoidal Choroidal Vasculopathy: the PALLAS Trial

Polypoidal Choroidal VasculopathyPolypoidal Choroidal Vasculopathy (PCV)
Yeungnam University College of Medicine50 enrolled1 locationNCT07389980
Recruiting
Not Applicable

Effects of Acute Sugar Intake on Choroidal Thickness

Choroid
Southern College of Optometry47 enrolled1 locationNCT07376005
Recruiting
Phase 1

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Central Nervous System NeoplasmsGlioblastomaOligodendroglioma+20 more
Jazz Pharmaceuticals102 enrolled1 locationNCT04541082
Recruiting

Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification

Germ Cell TumorGliomaEpendymoma+10 more
European Organisation for Research and Treatment of Cancer - EORTC1,650 enrolled42 locationsNCT05259605