Phase 2 Cirrhosis Clinical Trials
28 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 28 trials
Recruiting
Phase 2
A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)
Liver Cirrhosis
Boehringer Ingelheim30 enrolled27 locationsNCT07325526
Recruiting
Phase 2
Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement
CirrhosisHepatic Encephalopathy
Hunter Holmes Mcguire Veteran Affairs Medical Center30 enrolled1 locationNCT06052176
Recruiting
Phase 2
SAMe Trial for Patients With Alcoholic Cirrhosis
Alcoholic Cirrhosis
Indiana University196 enrolled2 locationsNCT04250259
Recruiting
Phase 1Phase 2
EUS Guided Portal-systemic Pressure Gradient Measurement
CirrhosisPortal Hypertension
Chinese University of Hong Kong30 enrolled1 locationNCT04633356
Recruiting
Phase 2
Statin and Beta Blocker Use in Patients With Decompensated Cirrhosis
CirrhosisDecompensated Cirrhosis of LiverDecompensated Liver Cirrhosis+1 more
CAMC Health System50 enrolled1 locationNCT06764966
Recruiting
Phase 2
Empagliflozin in Patients With Cirrhosis and Ascites
CirrhosisLiver Failure
Yale University20 enrolled1 locationNCT05726032
Recruiting
Phase 1Phase 2
Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells Injection in Patients With Decompensated Hepatitis B Cirrhosis
Decompensated Hepatitis B Cirrhosis
Beijing Tuohua Weiye Biotechnology Co., Ltd.76 enrolled1 locationNCT07413549
Recruiting
Phase 1Phase 2
RTX001 Autologous Engineered Macrophages for Liver Cirrhosis
Liver DiseasesCirrhosis, LiverDecompensated Liver Cirrhosis+5 more
Resolution Therapeutics Limited30 enrolled14 locationsNCT06823713
Recruiting
Phase 2
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
CirrhosisCirrhosis, LiverCirrhosis Due to Hepatitis B+5 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)256 enrolled13 locationsNCT05832229
Recruiting
Phase 2
Study of Tremelimumab and Durvalumab (MEDI4736) (T300+D) in Advanced Hepatocellular Carcinomas With Child-Pugh-B Cirrhosis
Hepatocellular CarcinomaCirrhosis, Liver
The University of Texas Health Science Center at San Antonio32 enrolled1 locationNCT06526104
Recruiting
Phase 2Phase 3
A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer
Hepatocellular CarcinomaCirrhosis
Inova Health Care Services12 enrolled2 locationsNCT06007846
Recruiting
Phase 2
Safety and Efficacy of Atorvastatin v. Placebo on HCC Risk
CirrhosisLiver Fibroses
Raymond Chung60 enrolled2 locationsNCT05028829
Recruiting
Phase 2
EGCG for Hepatocellular Carcinoma Chemoprevention
Cirrhosis, Liver
University of Texas Southwestern Medical Center60 enrolled1 locationNCT06015022
Recruiting
Phase 2
Danazol for Treatment of Cytopenias in Patients With Cirrhosis
Cirrhosis, LiverCytopenia
University of Southern California10 enrolled1 locationNCT04873102
Recruiting
Phase 1Phase 2
CRISPR-Edited HLA Donor Liver Transplant to Reduce Rejection
Liver CancerLiver MetastasesLiver Cirrhosis+4 more
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053488
Recruiting
Phase 2
Droxidopa to Increase Mean Arterial Pressure in Decompensated Cirrhosis Patients With Acute Kidney Injury
CirrhosisAcute Kidney InjuryDecompensated Cirrhosis of Liver
Giuseppe Cullaro, MD75 enrolled1 locationNCT06937307
Recruiting
Phase 1Phase 2
Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease
CirrhosisAlcohol Use DisorderLiver Disease; Alcohol-Related
Virginia Commonwealth University80 enrolled2 locationsNCT05548452
Recruiting
Phase 2
Effects of Metformin on Hepatic Venous Pressure Gradient in Patients With Cirrhosis and Portal Hypertension
CirrhosisPortal Hypertension Related to Cirrhosis
Assistance Publique - Hôpitaux de Paris76 enrolled1 locationNCT06687265
Recruiting
Phase 2
A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).
Liver CirrhosisDecompensated Cirrhosis of LiverAcute on Chronic Liver Failure (ACLF)
European Foundation for Study of Chronic Liver Failure90 enrolled9 locationsNCT05895136
Recruiting
Phase 2
Albumin Assisted Diuresis in Patients with Cirrhosis and Ascites
CirrhosisAscites Hepatic
Anahita Rabiee MD MHS20 enrolled1 locationNCT06812390