Phase 1 Complication Clinical Trials
19 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–19 of 19 trials
Recruiting
Phase 1
Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMO
Oxygen DeliveryCardiogenic ShockAnemia+2 more
University Hospital, Lille236 enrolled1 locationNCT05699005
Recruiting
Phase 1
Phase I Trial on the Safety of Delayed Infusion of a Naïve T Cell-Depleted Hematopoietic Graft With Memory T Cells in Solid Organ Transplant Recipients
Solid Organ Transplant ComplicationsSolid Organ Transplant RecipientsSolid Organ Transplant Rejection
Francisco Hernández Oliveros10 enrolled1 locationNCT06997471
Recruiting
Phase 1
Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon
Breast ReconstructionGenetic PredispositionPerfusion; Complications+1 more
Duke University25 enrolled1 locationNCT07264790
Recruiting
Phase 1Phase 2
Pilot Study of Preoperative Intestinal Training Using Antegrade Ileostomy Infusion
Stoma - IleostomyIleostomy; Complications
University of California, San Diego20 enrolled1 locationNCT06461559
Recruiting
Phase 1
S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion
Transfusion Related Complication
James Reynolds35 enrolled1 locationNCT03999229
Recruiting
Phase 1Phase 2
CMVIG Prophylaxis in Belatacept Conversion Kidney Transplant Recipients
Kidney Transplant; ComplicationsCMV
University of Minnesota30 enrolled1 locationNCT07096453
Recruiting
Phase 1Phase 2
Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial
Critical IllnessThoracic SurgeryPost-operative Complication
Wandercraft5 enrolled1 locationNCT07220733
Recruiting
Phase 1
IS-free Treg HaploHCT
Myelodysplastic SyndromesStem Cell Transplant ComplicationsGraft vs Host Disease+2 more
Dana-Farber Cancer Institute30 enrolled1 locationNCT04678401
Recruiting
Phase 1
Study on the Effect of Combined Estrogen and Progestogen Therapy on Endometrial Repair After Induced Abortion
Pregnancy Complications
Women's Hospital School Of Medicine Zhejiang University200 enrolled1 locationNCT06546397
Recruiting
Phase 1Phase 2
Minimally Invasive Esophagectomy Pain Control Trial
Postoperative ComplicationsPostoperative Pain, Acute
Swedish Medical Center30 enrolled1 locationNCT05906134
Recruiting
Phase 1Phase 2
Pilot Study of the α Prototype NIMBLE System: Feasibility, Safety, and Initial Performance in Non-Invasive Detection of Coronary In-Stent Restenosis
In-stent RestenosisStent FractureStent Complication
Nimble Diagnostics S.L.30 enrolled1 locationNCT06968858
Recruiting
Phase 1Phase 2
Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease
Post Operative PainUrolithiasisStent Complication+1 more
University of Texas Southwestern Medical Center80 enrolled1 locationNCT06158620
Recruiting
Phase 1
Efficacy of Adipose Tissue Derived Stem Cells for the Treatment of Diabetic Foot Ulcers
Diabetes MellitusDiabetic Foot UlcerDiabetic Foot+8 more
University of the Punjab28 enrolled1 locationNCT05610865
Recruiting
Phase 1Phase 2
Probiotics Combined with Enteral Nutrition Reduces Postoperative Infectious Complications in PD
Infectious Complications
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School68 enrolled1 locationNCT06719596
Recruiting
Phase 1
Safety of DNP007 in Healthy Subjects
Liver Transplant; ComplicationsSteatohepatitis, NonalcoholicLiver Transplant Rejection
Seoul National University Hospital12 enrolled1 locationNCT06400771
Recruiting
Phase 1
Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With Glioblastoma
GlioblastomaRadiotherapy; ComplicationsGlioblastoma Multiforme+2 more
Hospital San Carlos, Madrid12 enrolled1 locationNCT06418113
Recruiting
Phase 1Phase 2
LEARNER- Low dosE AspiRiN prEterm tRial (Angola)
Sickle Cell DiseasePregnancy ComplicationsPre-Eclampsia+1 more
Instituto Nacional de Investigacao em Saude, Angola450 enrolled1 locationNCT06417411
Recruiting
Phase 1Phase 2
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
Sexual DysfunctionAutoimmune DiseasesNeurologic Disorders+8 more
Thomas Advanced Medical LLC5,000 enrolled1 locationNCT04684602
Completed
Phase 1
A Single Center, Randomized, Double-Blind, Single-Dose, 2-Way Crossover, Dose Escalation Study of the Pharmacokinetics and Pharmacodynamics of PX811019 Compared with triethylenetetramine dihydrochloride in Normal Healthy Volunteers
Pharmacokinetics of a study drug for the treatment of diabetic complications
Protemix Corporation24 enrolled1 locationACTRN12612000738820