COPD Exacerbation Clinical Trials

18 recruiting

COPD Exacerbation Trials at a Glance

27 actively recruiting trials for copd exacerbation are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 18 trials, with the heaviest enrollment activity in London, Leicester, and Istanbul. Lead sponsors running copd exacerbation studies include Saglik Bilimleri Universitesi, Assiut University, and Asger Sverrild.

Browse copd exacerbation trials by phase

Treatments under study

About COPD Exacerbation Clinical Trials

Looking for clinical trials for COPD Exacerbation? There are currently 18 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new COPD Exacerbation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about COPD Exacerbation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 27 trials

Recruiting

Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting

AsthmaVasculitisInflammatory Disease+2 more
Imperial College London120 enrolled1 locationNCT05012033
Recruiting

Predicting Adverse Outcomes Using Machine Learning of COPD Patients in Hong Kong

COPD Exacerbation
Chinese University of Hong Kong100,000 enrolled1 locationNCT05825014
Recruiting
Not Applicable

Emotional-distress-based Integrated Care Programme in Patients With an Acute Exacerbation of COPD

COPD Exacerbation
University of Zurich20 enrolled1 locationNCT07351929
Recruiting
Not Applicable

Impact of a Multimodal Intervention on Antibiotic Prescribing for Respiratory Infections in Primary Care

AnginaAcute BronchiolitisAcute Bronchitis+8 more
University Hospital, Caen4,500 enrolled1 locationNCT07359287
Recruiting
Not Applicable

High-intensity Resistance Training in Post-exacerbation COPD

COPD Exacerbation
Istituti Clinici Scientifici Maugeri SpA64 enrolled1 locationNCT07302425
Recruiting
Not Applicable

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

MesotheliomaAtelectasisPneumothorax+11 more
Brigham and Women's Hospital230 enrolled1 locationNCT06538376
Recruiting
Not Applicable

DUET Versus Standard Interface for Hypercapnic COPD Patients

COPDCOPD ExacerbationHypercapnia
Larissa University Hospital50 enrolled2 locationsNCT05829083
Recruiting
Not Applicable

Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery

SurgeryCOPD ExacerbationAbdominal Obesity+1 more
François Lellouche10 enrolled1 locationNCT04136717
Recruiting
Not Applicable

Neuromuscular Electrical Stimulation in COPD/Community Acquired Pneumonia

COPD Exacerbation AcuteCommunity-acquired Pneumonia
University of Vermont8 enrolled1 locationNCT05452226
Recruiting
Phase 4

Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary Disease

COPD ExacerbationCOPD Exacerbation Acute
Central Denmark Region1,888 enrolled1 locationNCT05703919
Recruiting
Not Applicable

The Reducing REVISITS Study: A Cluster RCT

COPDCOPD Exacerbation Acute
University of Chicago24 enrolled1 locationNCT05568043
Recruiting
Not Applicable

Effect of Home Based Pulmonary Rehabilitation on Exacerbation and Hospital Admission in Severe COPD

COPD Exacerbation
Saglik Bilimleri Universitesi24 enrolled1 locationNCT05738720
Recruiting
Not Applicable

Impact of Continuous Positive Airway Pressure on the Occurrence of Acute Exacerbations of COPD in Patients With COPD-OSA Overlap Syndrome (CO-OS)

Sleep ApneaCOPD ExacerbationOverlap Syndrome
University Hospital, Angers500 enrolled15 locationsNCT05958563
Recruiting

Non-contact Proactive Remote Monitoring of COPD Exacerbations

COPD Exacerbation
Life Detection Technologies75 enrolled1 locationNCT05598983
Recruiting
Phase 3

Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease

COPDCOPD Exacerbation
Guy's and St Thomas' NHS Foundation Trust1,400 enrolled34 locationsNCT06347536
Recruiting
Not Applicable

Nasal High-Flow in COPD

COPD Exacerbation
Marieke Duiverman136 enrolled3 locationsNCT03564236
Recruiting
Not Applicable

Role of Oral Care in Prevention of Nosocomial Pneumonia Among COPD Patients

COPD ExacerbationNosocomial Pneumonia
Assiut University60 enrolled1 locationNCT06691399
Recruiting
Phase 2

Effects of Blocking TSLP on Airway Inflammation and the Epithelial Immune-response to Exacerbation Triggers in Patients With COPD

COPDCOPD ExacerbationImmune System Disorder+2 more
Asger Sverrild80 enrolled2 locationsNCT05507242
Recruiting

Assessing Optimal Inhaler Strategies During Acute Exacerbations of COPD (AECOPDs) Using Oscillometry

COPDCOPD Exacerbation Acute
McGill University Health Centre/Research Institute of the McGill University Health Centre43 enrolled1 locationNCT06495047
Recruiting
Not Applicable

Respiratory Support in Chronic Obstructive Pulmonary Disease (COPD) Patients

Chronic Obstructive Pulmonary DiseaseCOPD Exacerbation
Clinact400 enrolled1 locationNCT03890224