Phase 1 COPD Clinical Trials

13 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 113 of 13 trials

Recruiting
Phase 1

Impact of Eradication Therapy on Helicobacter Pylori Infection With Chronic Obstructive Pulmonary Disease:

Chronic Obstructive Pulmonary Disease (COPD)With Poitive H Pylori
Zagazig University54 enrolled1 locationNCT07574879
Recruiting
Phase 1

Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease

AsthmaCOPDCystic Fibrosis+4 more
Mario Castro, MD, MPH260 enrolled1 locationNCT04624490
Recruiting
Phase 1Phase 2

cfMSC Stem Cell Therapy Targeting COPD

Chronic Obstructive Pulmonary Disease (COPD)
Shenzhen Geno-Immune Medical Institute30 enrolled1 locationNCT07477600
Recruiting
Phase 1

A Phase I Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics for a Single Dose of HRS-9821 Powder for Inhalation and Inhalation Suspension Administered in Healthy Subjects and Multiple Doses in Patients With COPD.

COPD
Guangdong Hengrui Pharmaceutical Co., Ltd160 enrolled1 locationNCT07116915
Recruiting
Phase 1Phase 2

Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

Idiopathic Pulmonary FibrosisEmphysema or COPD
Paul Szabolcs8 enrolled2 locationsNCT03500731
Recruiting
Phase 1

A Study of BBT002 in Healthy Volunteers (HVs) and in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)
Bambusa Therapeutics68 enrolled11 locationsNCT07288554
Recruiting
Phase 1Phase 2

Impact of Long-acting Bronchodilator- -Corticoid Inhaled Therapy on Ventilation, Lung Function and Breathlessness

COPD
University Hospital, Lille35 enrolled1 locationNCT06110403
Recruiting
Phase 1

A Clinical Study of TQC3721 Inhalation Powder in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.72 enrolled1 locationNCT06748079
Completed
Phase 1

Comparative assessment of the absorption of a generic formulation of tiotropium test product 1 and tiotropium test product 2 against the innovator Spiriva HandiHaler conducted under fasting conditions in healthy male and female volunteers

Bioavailability study conducted in healthy volunteers comparing three formulations of tiotropium with no health condition or problem studied. Tiotropium is a long-acting, antimuscarinic agent, which is often referred to as an anticholinergic and is used to make breathing easier for people with Chronic Obstructive Pulmonary Disease (COPD).
Zenith Technology Corp Ltd24 enrolled1 locationACTRN12615000073505
Recruiting
Phase 1

A Phase I Study to Evaluate the Safety and Efficacy of Mesenchymal Stromal Cells (MSC) for Treating Chronic Obstructive Pulmonary Disease (COPD)

COPD
Royal Perth Hospital10 enrolled1 locationACTRN12614000731695
Completed
Phase 1

Randomised trial comparing controlled oxygen therapy with high-flow oxygen therapy in the treatment of patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) in the pre-hospital setting

Chronic Obstructive Pulmonary Disease (COPD)
Associate Professor Richard Wood-Baker150 enrolled1 locationACTRN12609000236291
Completed
Phase 1

Trial of nurse and GP partnership for care of COPD

Chronic Obstructive Pulmonary Disease (COPD)
Prof Nicholas Zwar400 enrolled1 locationACTRN12606000304538
Recruiting
Phase 1

Randomised controlled trial of arm training in patients with COPD

Chronic obstructive pulmonary disaese (COPD)
Department of Respiratory Medicine, Royal Prince Alfred Hospital60 enrolled1 locationACTRN12605000679684