Phase 2 Dementia Clinical Trials
45 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 45 trials
Recruiting
Phase 2
Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis
Lewy Body Dementia Psychosis
ACADIA Pharmaceuticals Inc.180 enrolled54 locationsNCT07029581
Recruiting
Phase 2Phase 3
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
Agitation Associated With Alzheimer's Disease Dementia
Exciva GmbH300 enrolled14 locationsNCT07284472
Recruiting
Phase 2
Fisetin in Mild Alzheimer's Disease
Alzheimer DiseaseAlzheimer DementiaAlzheimer Dementia (AD)+4 more
Sunnybrook Health Sciences Centre5 enrolled1 locationNCT07279714
Recruiting
Phase 2
Clinical Trial Evaluating the Efficacy of AGB101 for Reducing Hippocampal Overactivity in Older Adults
DementiaHippocampal Overactivity
Johns Hopkins University60 enrolled1 locationNCT06919926
Recruiting
Phase 2
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
DementiaHealthy VolunteersAlzheimer Disease+1 more
Akiva Mintz200 enrolled1 locationNCT07012993
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)
Frontotemporal DementiaFTDDementia, Frontotemporal+1 more
AviadoBio Ltd18 enrolled19 locationsNCT06064890
Recruiting
Phase 1Phase 2
Rifaximin SSD in Dementia Trial
Dementia Alzheimer TypeDementia Associated With Cerebrovascular Disease
Jasmohan Bajaj20 enrolled1 locationNCT06718686
Recruiting
Phase 2
18F-mFBG Cardiac Uptake With Lewy Body Dementia
Lewy Body Dementia (LBD)Parkinson Disease (PD)
Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)20 enrolled1 locationNCT07176286
Recruiting
Phase 2
Efficacy Biomarkers of DAOIB for Dementia
Dementia
Chang Gung Memorial Hospital123 enrolled2 locationsNCT05582161
Recruiting
Phase 2
Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease
Alzheimer DementiaLate Onset Alzheimer DiseaseNeurodegenerative Diseases
University of Arizona100 enrolled10 locationsNCT04838301
Recruiting
Phase 2
Testing the Pain Clinical Practice Guideline
PainDementia
University of Maryland, Baltimore300 enrolled7 locationsNCT05858996
Recruiting
Phase 2Phase 3
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
DementiaAlzheimers DiseaseAlzheimers Disease, Familial
Washington University School of Medicine280 enrolled35 locationsNCT05552157
Recruiting
Phase 2Phase 3
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
DementiaAlzheimers DiseaseAlzheimers Disease, Familial
Washington University School of Medicine280 enrolled35 locationsNCT06647498
Recruiting
Phase 2
Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease
DementiaAlzheimers DiseaseMild Cognitive Impairment Due to Alzheimer's Disease
Brigham and Women's Hospital16 enrolled1 locationNCT06489548
Recruiting
Phase 1Phase 2
Deep Repetitive Transcranial Magnetic Stimulation (rTMS) of the Precuneus for Alzheimer Disease (AD)
Alzheimer DiseaseAlzheimer&Amp;Amp;#39;s DiseaseDementia Alzheimer Type+4 more
University of California, Los Angeles54 enrolled1 locationNCT06597942
Recruiting
Phase 2
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
Agitation Associated With Alzheimer's Dementia
Intra-Cellular Therapies, Inc.320 enrolled69 locationsNCT06651567
Recruiting
Phase 1Phase 2
A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes
Frontotemporal DementiaFTDFTD-GRN
Passage Bio, Inc.30 enrolled10 locationsNCT04747431
Recruiting
Phase 2
A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease Dementia
Agitation Associated With Alzheimer's Disease Dementia
Ono Pharmaceutical Co., Ltd.90 enrolled38 locationsNCT06803823
Recruiting
Phase 2
Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia
Alzheimer DiseaseAlzheimer DementiaAlzheimer Dementia (AD)+3 more
Sunnybrook Health Sciences Centre12 enrolled1 locationNCT07279740
Recruiting
Phase 1Phase 2
Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments
Parkinson DiseaseParkinson Disease Dementia
Prabesh Kanel45 enrolled1 locationNCT07154511