Phase 2 Dementia Clinical Trials
49 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 49 trials
Recruiting
Phase 2
Mindful Walking Neural Correlates of Executive Function in SC Older Adults at Risk of Dementias
Older Adults With Elevated Dementia Risk
University of South Carolina54 enrolled1 locationNCT07638046
Recruiting
Phase 1Phase 2
Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease
Alzheimer Dementia (AD)
The Methodist Hospital Research Institute30 enrolled1 locationNCT07651319
Recruiting
Phase 2Phase 3
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
Agitation Associated With Alzheimer's Disease Dementia
Exciva GmbH300 enrolled49 locationsNCT07284472
Recruiting
Phase 2
Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis
Lewy Body Dementia Psychosis
ACADIA Pharmaceuticals Inc.180 enrolled56 locationsNCT07029581
Recruiting
Phase 2
Human Mesenchymal Stem Cells (hMSC) in Behavioral Problems Due to Alzheimer's Disease.
Alzheimer DiseaseAgitation in Dementia
Bernard (Barry) Baumel8 enrolled1 locationNCT06781333
Recruiting
Phase 2
A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease Dementia
Agitation Associated With Alzheimer's Disease Dementia
Ono Pharmaceutical Co., Ltd.90 enrolled38 locationsNCT06803823
Recruiting
Phase 2
Testing the Pain Clinical Practice Guideline
PainDementia
University of Maryland, Baltimore300 enrolled11 locationsNCT05858996
Recruiting
Phase 1Phase 2
Ferritin and Iron Burden in SAH sIRB
DementiaSAH
Duke University66 enrolled2 locationsNCT03754725
Recruiting
Phase 2
Ambroxol in New and Early DLB, A Phase IIa Multicentre Randomized Controlled Double Blind Clinical Trial
Dementia With Lewy Bodies
Helse Fonna180 enrolled8 locationsNCT04588285
Recruiting
Phase 2
Fisetin in Mild Alzheimer's Disease
Alzheimer DiseaseAlzheimer DementiaAlzheimer Dementia (AD)+4 more
Sunnybrook Health Sciences Centre5 enrolled1 locationNCT07279714
Recruiting
Phase 2
Clinical Trial Evaluating the Efficacy of AGB101 for Reducing Hippocampal Overactivity in Older Adults
DementiaHippocampal Overactivity
Johns Hopkins University60 enrolled1 locationNCT06919926
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)
Frontotemporal DementiaFTDDementia, Frontotemporal+1 more
AviadoBio Ltd18 enrolled19 locationsNCT06064890
Recruiting
Phase 2
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
DementiaHealthy VolunteersAlzheimer Disease+1 more
Akiva Mintz200 enrolled1 locationNCT07012993
Recruiting
Phase 1Phase 2
Rifaximin SSD in Dementia Trial
Dementia Alzheimer TypeDementia Associated With Cerebrovascular Disease
Jasmohan Bajaj20 enrolled1 locationNCT06718686
Recruiting
Phase 2
18F-mFBG Cardiac Uptake With Lewy Body Dementia
Lewy Body Dementia (LBD)Parkinson Disease (PD)
Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)20 enrolled1 locationNCT07176286
Recruiting
Phase 2
Efficacy Biomarkers of DAOIB for Dementia
Dementia
Chang Gung Memorial Hospital123 enrolled2 locationsNCT05582161
Recruiting
Phase 2
Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease
Alzheimer DementiaLate Onset Alzheimer DiseaseNeurodegenerative Diseases
University of Arizona100 enrolled10 locationsNCT04838301
Recruiting
Phase 2
Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia
fronto-temporal dementiaFrontotemporal DementiaFrontotemporal Degeneration+3 more
Johns Hopkins University50 enrolled1 locationNCT06604520
Recruiting
Phase 2Phase 3
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
DementiaAlzheimers DiseaseAlzheimers Disease, Familial
Washington University School of Medicine280 enrolled35 locationsNCT05552157
Recruiting
Phase 2Phase 3
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
DementiaAlzheimers DiseaseAlzheimers Disease, Familial
Washington University School of Medicine280 enrolled35 locationsNCT06647498