Phase 1 Diabetes Mellitus, Type 2 Clinical Trials

12 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 112 of 12 trials

Recruiting
Phase 1

A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus

ObesityDiabetes Mellitus, Type 2Overweight
Eli Lilly and Company40 enrolled1 locationNCT07299084
Recruiting
Phase 1Phase 2

A First-In-Human Study of ARO-ALK7 in Adults With Obesity With and Without Type 2 Diabetes Mellitus

ObesityDiabetes Mellitus, Type 2
Arrowhead Pharmaceuticals138 enrolled8 locationsNCT06937203
Recruiting
Phase 1

A Study of LY4057996 in Healthy Participants and Participants With Type 1 and Type 2 Diabetes

Diabetes Mellitus, Type 2Diabetes Mellitus, Type 1
Eli Lilly and Company124 enrolled1 locationNCT06945406
Recruiting
Phase 1

Multiple Dose Study of MK-2828 in Participants With Type 2 Diabetes (MK-2828-003)

Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC64 enrolled11 locationsNCT07089784
Recruiting
Phase 1

A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006)

Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC52 enrolled4 locationsNCT07242469
Recruiting
Phase 1

Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II

Diabetes Mellitus, Type 2Type 2 DiabetesAspirin+2 more
Montreal Heart Institute30 enrolled1 locationNCT05702463
Recruiting
Phase 1

A Study to Test How Insulin NNC0471-0119 H Works in the Body in Participants With Type 2 Diabetes When Given by an Insulin Pump

Diabetes Mellitus, Type 2
Novo Nordisk A/S65 enrolled1 locationNCT07068295
Recruiting
Phase 1Phase 2

Doxycycline in Type II Diabetes

Diabetes Mellitus, Type 2
Mostafa Bahaa60 enrolled1 locationNCT06329882
Recruiting
Phase 1

To Compare the Safety and PK/PD Characteristics of Subjects With Between Hepatic Impairment and Normal Hepatic Function

Diabetes Mellitus, Type 2
Daewoong Pharmaceutical Co. LTD.24 enrolled1 locationNCT05747664
Recruiting
Phase 1

A Study to Investigate the Safety, Tolerability, Pharmacokinetic/Pharmacodynamic Characteristics and Food Effect of HGR4113 in Healthy Subjects

Diabetes Mellitus, Type 2
Glaceum40 enrolled1 locationNCT05642377
Recruiting
Phase 1

Arterial Ablation for the Treatment of Type 2 Diabetes Mellitus and Its Comorbidities

HypertensionDiabetes Mellitus, Type 2
Neurotronic, Inc.50 enrolled3 locationsNCT05363761
Recruiting
Phase 1

Ablation of Arteries for the Treatment of Type 2 Diabetes Mellitus and Its Comorbidities

HypertensionDiabetes Mellitus, Type 2
Neurotronic, Inc.60 enrolled3 locationsNCT05369065