Dilated Cardiomyopathy Clinical Trials

45 recruitingLast updated: July 11, 2026

There are 45 actively recruiting dilated cardiomyopathy clinical trials across 25 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4. Top locations include Houston, Texas, United States, Cincinnati, Ohio, United States, Chicago, Illinois, United States. Updated daily from ClinicalTrials.gov.


Dilated Cardiomyopathy Trials at a Glance

45 actively recruiting trials for dilated cardiomyopathy are listed on ClinicalTrialsFinder across 6 cities in 25 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Houston, Cincinnati, and Chicago. Lead sponsors running dilated cardiomyopathy studies include Chinese Academy of Medical Sciences, Fuwai Hospital, Second Affiliated Hospital, School of Medicine, Zhejiang University, and Tomsk National Research Medical Center of the Russian Academy of Sciences.

Browse dilated cardiomyopathy trials by phase

Treatments under study

About Dilated Cardiomyopathy Clinical Trials

Looking for clinical trials for Dilated Cardiomyopathy? There are currently 20 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Dilated Cardiomyopathy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Dilated Cardiomyopathy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 45 trials

Recruiting
Phase 1Phase 2

An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM)

Dilated Cardiomyopathy (DCM)BAG3 Mutation Associated Dilated Cardiomyopathy
Affinia Therapeutics22 enrolled3 locationsNCT07426419
Recruiting
Phase 1Phase 2

A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)

LMNA-Related Dilated Cardiomyopathy
Nuevocor Pte. Ltd.21 enrolled6 locationsNCT07606274
Recruiting
Phase 1

Safety and Efficacy of Second Infusion of FAP iCDC in End-stage Dilated Cardiomyopathy

Heart FailureDilated Cardiomyopathy (DCM)
Second Affiliated Hospital, School of Medicine, Zhejiang University5 enrolled1 locationNCT07516288
Recruiting
Phase 1

A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy

Dilated Cardiomyopathy (DCM)
Rocket Pharmaceuticals Inc.8 enrolled3 locationsNCT07137338
Recruiting
Phase 1

A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM)

Dilated Cardiomyopathy
Emory University36 enrolled5 locationsNCT06464588
Recruiting

Pediatric Cardiomyopathy Mutation Analysis

CardiomyopathiesHypertrophic CardiomyopathyDilated Cardiomyopathy+3 more
Indiana University300 enrolled1 locationNCT02432092
Recruiting
Phase 1

A Study of AZD4063 in PLN R14del Dilated Cardiomyopathy

Dilated Cardiomyopathy
AstraZeneca31 enrolled4 locationsNCT07241104
Recruiting
Phase 1Phase 2

ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy

BAG3 Mutation Associated Dilated Cardiomyopathy
Alexion Pharmaceuticals, Inc.6 enrolled10 locationsNCT07218887
Recruiting
Phase 2Phase 3

A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

Symptomatic Genetic Dilated Cardiomyopathy
Kardigan, Inc.332 enrolled43 locationsNCT07210723
Recruiting

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

Heart FailureCardiotoxicityMyocardial Infarction+12 more
Peerbridge Health, Inc2,000 enrolled8 locationsNCT06699056
Recruiting
Not Applicable

High Fat Diet for Cardiac Metabolic Reprogramming

Heart Failure With Reduced Ejection FractionNon-ischemic Dilated Cardiomyopathy
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III80 enrolled5 locationsNCT06747429
Recruiting

Mayo AVC Registry and Biobank

CardiomyopathiesCardiovascular DiseasesSarcoidosis+14 more
Mayo Clinic1,000 enrolled2 locationsNCT03049254
Recruiting
Phase 2

Administration of Allogeneic-MSC in Patients With Non-Ischemic Dilated Cardiomyopathy

Non-ischemic Dilated Cardiomyopathy
Joshua M Hare136 enrolled4 locationsNCT04476901
Recruiting
Not Applicable

Modifying Factors in Striated Muscle Laminopathies

LaminopathiesEmery Dreifuss Muscular Dystrophy 2LMNA-Related Congenital Muscular Dystrophy+1 more
Institut National de la Santé Et de la Recherche Médicale, France40 enrolled8 locationsNCT05394506
Recruiting

Study of the Progression of Chronic Cardiovascular Conditions

Heart FailureHypertensionDilated Cardiomyopathy+9 more
Prolaio5,000 enrolled1 locationNCT07420907
Recruiting

Multimodal Analysis of Endomyocardial Biopsies

CardiomyopathiesHypertrophic Cardiomyopathy (HCM)Heart Transplantation+4 more
University Hospital, Essen216 enrolled1 locationNCT07359690
Recruiting

The Application of T1 Mapping in Real-World

Hypertrophic Cardiomyopathy (HCM)MyocarditisMyocardial Infarction (MI)+2 more
Chinese Academy of Medical Sciences, Fuwai Hospital2,000 enrolled1 locationNCT07354646
Recruiting

Prognostic Values of Coronary Microvascular Dysfunction in Patients With Dilated Cardiomyopathy

Dilated Cardiomyopathy (DCM)
Second Affiliated Hospital, School of Medicine, Zhejiang University330 enrolled1 locationNCT07293338
Recruiting
Not Applicable

Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study

Heart Failure With Reduced Ejection Fraction (HFrEF)Dilated Cardiomyopathy
Ancora Heart, Inc.400 enrolled132 locationsNCT04331769
Recruiting
Not Applicable

Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure Patients

Heart FailureNon-ischemic Dilated CardiomyopathyLeft Bundle-Branch Block+4 more
Tomsk National Research Medical Center of the Russian Academy of Sciences60 enrolled1 locationNCT05769036