Phase 2 Epilepsy Clinical Trials
30 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 30 trials
Recruiting
Phase 2Phase 3
A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
Focal Epilepsy
Biohaven Therapeutics Ltd.390 enrolled124 locationsNCT06132893
Recruiting
Phase 2
Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy
EpilepsySeizures, Epileptic
Supernus Pharmaceuticals, Inc.60 enrolled10 locationsNCT05518578
Recruiting
Phase 2Phase 3
Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
Focal Epilepsy
Biohaven Therapeutics Ltd.390 enrolled174 locationsNCT06309966
Recruiting
Phase 1Phase 2
A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy
EpilepsyDrug Resistant EpilepsySeizures, Focal
NaviFUS Corporation8 enrolled3 locationsNCT06388707
Recruiting
Phase 1Phase 2
AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
Mesial Temporal Lobe Epilepsy
UniQure Biopharma B.V.12 enrolled18 locationsNCT06063850
Recruiting
Phase 2
A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures
EpilepsyRefractory Focal EpilepsyFocal Epilepsy
Rapport Therapeutics Inc.30 enrolled7 locationsNCT07219407
Recruiting
Phase 2
Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study
EpilepsyTuberous Sclerosis Complex
Darcy Krueger64 enrolled11 locationsNCT05104983
Recruiting
Phase 1Phase 2
Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders.
EpilepsyHyperkinesisGNAO1
Pirogov Russian National Research Medical University5 enrolled1 locationNCT07363603
Recruiting
Phase 1Phase 2
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
Epilepsy, Temporal Lobe
Neurona Therapeutics10 enrolled17 locationsNCT06422923
Recruiting
Phase 2
An Open-label Study to Evaluate Safety, Tolerability, and Efficacy of CB03-154 in Subjects Diagnosed With Epilepsy
Focal Epilepsy
Shanghai Zhimeng Biopharma, Inc.144 enrolled1 locationNCT07238868
Recruiting
Phase 2
A Study Evaluating NPT 2042 Versus Placebo in Subjects Aged 16-75 Years With Genetic Generalized Epilepsy (GGE) and Absence Seizures
Epilepsy, GeneralizedEpilepsy, Absence
NeuroPro Therapeutics, Inc.10 enrolled1 locationNCT06769659
Recruiting
Phase 1Phase 2
A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy
EpilepsySCN2A-DEE
Praxis Precision Medicines60 enrolled3 locationsNCT05737784
Recruiting
Phase 2
The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy
Drug Resistant Epilepsy
Madeline Fields8 enrolled1 locationNCT05019885
Recruiting
Phase 2
Enhanced MRI Imaging in Healthy Participants and Participants With Epilepsy
Epilepsy, Temporal Lobe
University of Alberta50 enrolled1 locationNCT06483061
Recruiting
Phase 2
An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures
Focal Onset SeizurePrimary Generalized Epilepsy
Praxis Precision Medicines50 enrolled11 locationsNCT06908356
Recruiting
Phase 2Phase 3
Exogenous Ketone Esters for Drug Resistant Epilepsy
Drug Resistant Epilepsy
Sohag University60 enrolled1 locationNCT05670847
Active
Phase 2
Efficacy And Withdrawal Symptoms in Transition Between Cannabidivarin (CBDV) and Cannabidiol (CBD) in Children with Rett Syndrome and Refractory Epilepsy
Refractory EpilepsyRett Syndrome
Sydney Children's Hospital Network3 enrolled1 locationACTRN12624000948594
Recruiting
Phase 2
Clinical Study Evaluating Safety of Pentoxifylline and Celecoxib in Patients With Grand-Mal Epilepsy Treated by Phenytoin Monotherapy
Epilepsy
Mostafa Bahaa90 enrolled1 locationNCT05637086
Recruiting
Phase 2
Treating Postictal Symptoms Using Ibuprofen and Nifedipine
EpilepsyEpilepsies, Partial
University of Calgary90 enrolled2 locationsNCT03949478
Recruiting
Phase 2
A Phase 2A, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety and Pharmacokinetics of ES-481 in Adult Patients with Drug Resistant Epilepsy.
Epilepsy
ES Therapeutics Australia Pty Ltd24 enrolled4 locationsACTRN12621000033842