Phase 3 Epilepsy Clinical Trials
17 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–17 of 17 trials
Recruiting
Phase 2Phase 3
A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
Focal Epilepsy
Biohaven Therapeutics Ltd.390 enrolled124 locationsNCT06132893
Recruiting
Phase 2Phase 3
Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
Focal Epilepsy
Biohaven Therapeutics Ltd.390 enrolled174 locationsNCT06309966
Recruiting
Phase 3
A Study to Test the Long-term Safety and Tolerability of Brivaracetam in Study Participants With Childhood Absence Epilepsy or Juvenile Absence Epilepsy
Childhood Absence EpilepsyJuvenile Absence Epilepsy
UCB Biopharma SRL120 enrolled23 locationsNCT06315322
Recruiting
Phase 3
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
Mesial Temporal Lobe Epilepsy
Neurona Therapeutics88 enrolled33 locationsNCT05135091
Recruiting
Phase 3
Double-blind, Randomized Clinical Trial Evaluating the Efficacy and Safety of Vormatrigine in Adults With Focal Seizures
Focal Epilepsy
Praxis Precision Medicines300 enrolled7 locationsNCT07505004
Recruiting
Phase 3
Levetiracetam Three Times Daily in Epilepsy
Epilepsy
Waad Alkathiri120 enrolled1 locationNCT07490769
Recruiting
Phase 3
TAP-GRIN: Interventional Study on Patients With GRIN-related Neurodevelopmental Disorders
EpilepsyNeurodevelopmental Disorder (Diagnosis)GRIN-related Disorders+4 more
Meyer Children's Hospital IRCCS40 enrolled3 locationsNCT07377032
Recruiting
Phase 3
LEvetiracetam to Prevent Seizures in Symptomatic Alzheimer's Disease in Adults With Down Syndrome
EpilepsyAlzheimer DiseaseSeizures+7 more
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau120 enrolled5 locationsNCT07234695
Recruiting
Phase 3
A Study to Test the Safety and Tolerability of Brivaracetam in Children and Adolescents With Seizures
Epilepsy
UCB Biopharma SRL70 enrolled36 locationsNCT04715646
Recruiting
Phase 3
ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures.
Epilepsy, Generalized
Ono Pharmaceutical Co., Ltd.15 enrolled25 locationsNCT06579573
Recruiting
Phase 3
Lemborexant Treatment of Insomnia Linked to Epilepsy
EpilepsySleep
University of Manitoba26 enrolled2 locationsNCT06262594
Recruiting
Phase 2Phase 3
Exogenous Ketone Esters for Drug Resistant Epilepsy
Drug Resistant Epilepsy
Sohag University60 enrolled1 locationNCT05670847
Recruiting
Phase 3
Biperiden Trial for Epilepsy Prevention
Brain Injury Traumatic SevereBrain Injury Traumatic ModeratePost Traumatic Epilepsy
Hospital Sirio-Libanes312 enrolled10 locationsNCT04945213
Terminated
Phase 3
Carisbamate Retention Study (CaReS): Comparative Study on the Long Term Effectiveness, Safety and Tolerability of Carisbamate Compared to Two Other Frequently Prescribed Anti-Epileptic Drugs (AEDs) in Patients With Epilepsy.
Epilepsy Seizures
Ortho-McNeil Janssen Scientific Affairs, LLC600 enrolled19 locationsACTRN12609000600246
Terminated
Phase 3
Open label extension study following a double-blind, randomized, placebo-controlled, multicenter study to assess the efficacy and safety of adjunctive zonisamide in primary generalized tonic-clonic seizures.
Epilepsy
Eisai Ltd154 enrolled12 locationsACTRN12608000516381
Terminated
Phase 3
A double blind, randomised, placebo controlled, multi centre study to assess the efficacy and safety of adjunctive zonisamide in myoclonic seizures associated with idiopathic generalised epilepsy.
Epilepsy
Eisai Ltd.110 enrolled12 locationsACTRN12608000097347
Completed
Phase 3
Efficacy & Safety of Zonisamide in newly diagnosed partial epilepsy patients.
Newly diagnosed partial epilepsy
Eisai Ltd582 enrolled1 locationACTRN12607000142437