Phase 4 ESS Clinical Trials
223 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 223 trials
Recruiting
Phase 4
Examining the Effects of Estradiol on Neural and Molecular Response to Reward
DepressionAnhedoniaPsychosis
University of North Carolina, Chapel Hill103 enrolled1 locationNCT05282277
Recruiting
Phase 4
Calfactant vs Poractant Alfa Using a Less Invasive Technique in Preterm Infants With Respiratory Distress Syndrome
SurfactantRespiratory Distress Syndrome in Premature InfantsRespiratory Distress Syndrome (RDS)
Uludag University234 enrolled5 locationsNCT07350018
Recruiting
Phase 4
Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression
Major Depressive DisorderChronic Major Depression, Recurrent
University of Texas at Austin50 enrolled1 locationNCT05892744
Recruiting
Phase 4
Algorithm Guided Treatment Versus Treatment as Usual (TAU) for Patients With Treatment Resistant Depression
Treatment Resistant Depression (TRD)
Aalborg University Hospital80 enrolled1 locationNCT07080723
Recruiting
Phase 4
Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients
Critical Illness
Scarborough General Hospital3,253 enrolled6 locationsNCT07173855
Recruiting
Phase 4
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Ocrelizumab in Participants With Relapsing Multiple Sclerosis and Primary Progressive Multiple Sclerosis
Relapsing Multiple SclerosisPrimary Progressive Multiple Sclerosis
Hoffmann-La Roche60 enrolled17 locationsNCT07483450
Recruiting
Phase 4
Effects of DaxibotulinumtoxinA for Blepharospasm and Hemifacial Spasm
Benign Essential BlepharospasmHemifacial Spasm
Montefiore Medical Center40 enrolled1 locationNCT06195241
Recruiting
Phase 4
Predictors of Improvements in Irritability and Aggression in Children With ADHD Treated With CNS Stimulants
ADHD - Attention Deficit Disorder With HyperactivityIrritabilityAggression Childhood
Milton S. Hershey Medical Center136 enrolled1 locationNCT06871488
Recruiting
Phase 4
A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
SchizophreniaMajor Depressive DisorderBipolar Disorder+2 more
Neurocrine Biosciences50 enrolled19 locationsNCT07105111
Recruiting
Phase 4
A Study of Esketamine Nasal Spray in Korean Participants With Treatment-resistant Depression
Depressive Disorder, Treatment-Resistant
Janssen Korea, Ltd., Korea47 enrolled6 locationsNCT07053345
Recruiting
Phase 4
Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care
Smoking CessationHuman Immunodeficiency Virus (HIV)
New York University500 enrolled1 locationNCT06598397
Recruiting
Phase 4
The Avenues Study: Dual Use Cessation
Smoking CessationElectronic Cigarette Use
University of Wisconsin, Madison500 enrolled1 locationNCT06474299
Recruiting
Phase 4
Sore Throat After Open Neck Elective Surgery
Postoperative Sore Throat, Cough, HoarsenessThyroid and Parathyroid Surgery
Saint Petersburg State University, Russia764 enrolled1 locationNCT07124650
Recruiting
Phase 4
Identifying and Treating Depression in the Orthopaedic Trauma Population
Depression
Wake Forest University Health Sciences100 enrolled1 locationNCT05976347
Recruiting
Phase 4
The Effect of Rifabutin in Mycobacterium Abscessus With Inducible Clarithromycin Resistance
Mycobacterium Abscessus Lung Disease
National Taiwan University Hospital60 enrolled1 locationNCT07514364
Recruiting
Phase 4
Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)
Desmoid TumorAggressive Fibromatosis
SpringWorks Therapeutics, Inc.50 enrolled21 locationsNCT07176689
Recruiting
Phase 4
Immunogenicity and Safety PCV-20 of the Vaccine Administered During an Acute Febrile Illness in Adults
Pneumococcal InfectionsAcute Febrile Illness
Centre Hospitalier Universitaire de Saint Etienne1,052 enrolled24 locationsNCT06822907
Recruiting
Phase 4
NPWTi on Closure of Chronic Pressure Sores
Pressure Sore
Northwestern University62 enrolled1 locationNCT05598398
Recruiting
Phase 4
Pragmatic Evaluation of Respiratory Distress Syndrome Treatment in Africa
Premature BirthRespiratory Distress Syndrome in Premature InfantSurfactant Deficiency Syndrome Neonatal+1 more
Indiana University1,512 enrolled8 locationsNCT06554522
Recruiting
Phase 4
Forebrain Electroneutral Transporters in Salt-sensitive Hypertension: an MRI Study
Salt-Sensitivity of Blood Pressure
University of Delaware120 enrolled1 locationNCT06094816