Phase 4 ESS Clinical Trials
250 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 250 trials
Recruiting
Phase 4
A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
SchizophreniaMajor Depressive DisorderBipolar Disorder+2 more
Neurocrine Biosciences50 enrolled22 locationsNCT07105111
Recruiting
Phase 4
The Association Between Bilateral Intermediate Cervical Plexus Block During Total Thyroidectomy and Surgical Stress Response
surgical stress responseThyroid CancerThyroid and Parathyroid Surgery+1 more
University Hospital Dubrava48 enrolled1 locationNCT07600580
Recruiting
Phase 4
Computational Assessment of GABA Receptor Modulation in PTSD
Stress Disorders, Post-Traumatic
VA Office of Research and Development150 enrolled1 locationNCT06852469
Recruiting
Phase 4
Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)
Major Depressive Disorder
Nova Scotia Health Authority400 enrolled10 locationsNCT05017311
Recruiting
Phase 4
The Effect of Rifabutin in Mycobacterium Abscessus With Inducible Clarithromycin Resistance
Mycobacterium Abscessus Lung Disease
National Taiwan University Hospital60 enrolled1 locationNCT07514364
Recruiting
Phase 4
A Study of Esketamine Nasal Spray in Korean Participants With Treatment-resistant Depression
Depressive Disorder, Treatment-Resistant
Janssen Korea, Ltd., Korea47 enrolled6 locationsNCT07053345
Recruiting
Phase 4
Eduction in ImmunoSuppressive Regimen Among Kidney Transplant Recipients Patients Admitted to the Intensive Care Unit for Septic Shock and/or Acute Respiratory Failure
Acute Respiratory FailureKidney Transplant RecipientsSepsis and septic shock+1 more
University Hospital, Strasbourg, France212 enrolled1 locationNCT06881927
Recruiting
Phase 4
Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia
Knee Stiffness After Total Knee Arthroplasty
Duke University128 enrolled1 locationNCT07348614
Recruiting
Phase 4
Long-Term Low-Intervention SafEty and Clinical Outcomes Clinical Study of LivmArli® in Patients With Alagille Syndrome or Progressive Familial Intrahepatic Cholestasis in the European Union (LEAP-EU)
Progressive Familial Intrahepatic CholestasisAlagille Syndrome
Mirum Pharmaceuticals, Inc.230 enrolled15 locationsNCT07290257
Recruiting
Phase 4
Treatment of Anaemia After Caesarean With Intravenous Versus Oral Iron and Postpartum Depression
Postpartum Depression (PPD)
Assistance Publique - Hôpitaux de Paris2,860 enrolled1 locationNCT06833788
Recruiting
Phase 4
Effect of the Traditional Chinese Medicine Yufeng Ningxin in Patients With Hypertension
HypertensionEssential (Primary) Hypertension
Beijing Anzhen Hospital350 enrolled16 locationsNCT07607275
Recruiting
Phase 4
Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant Depression
Treatment Resistant Depression
The George Institute162 enrolled7 locationsNCT06278779
Recruiting
Phase 4
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Ocrelizumab in Participants With Relapsing Multiple Sclerosis and Primary Progressive Multiple Sclerosis
Relapsing Multiple SclerosisPrimary Progressive Multiple Sclerosis
Hoffmann-La Roche60 enrolled17 locationsNCT07483450
Recruiting
Phase 4
Identifying and Treating Depression in the Orthopaedic Trauma Population
Depression
Wake Forest University Health Sciences100 enrolled1 locationNCT05976347
Recruiting
Phase 4
Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled Trial
DexmedetomidineLignocaineLaryngoscopic Stress Response
Rawalpindi Institute of Cardiology70 enrolled1 locationNCT07611890
Recruiting
Phase 4
The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery
Acute Kidney Injury (AKI)AnesthesiaMyocardial Injury After Noncardiac Surgery (MINS)+4 more
University of California, San Francisco18,000 enrolled10 locationsNCT06802224
Recruiting
Phase 4
Duration of Surfactant Administration and Impact on Stabilisation of Vital Parameters in Very Preterm Neonates: 1 Minutes Versus 5 Minutes
Cerebral oxygen saturationInfant Respiratory Distress SyndromeCerebral Oxygenation+3 more
Medical University of Graz76 enrolled1 locationNCT07261787
Recruiting
Phase 4
Evaluation of Efficacy of Skål Pro Powder on Symptoms of Irritable Bowel Syndrome
Pathologic ProcessesIntestinal DiseaseGastrointestinal Diseases+5 more
EP Plus Group Sdn Bhd60 enrolled1 locationNCT06271538
Recruiting
Phase 4
The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance Outcomes
Acute Stress ReactionFear of Spiders
Walter Reed Army Institute of Research (WRAIR)88 enrolled1 locationNCT06982183
Recruiting
Phase 4
Efficacy and Safety of Cerebrolysin on Prolonged Disorders of Consciousness
Disorder of ConsciousnessHemorrhagic Stroke
Konkuk University Medical Center12 enrolled1 locationNCT04427241