RecruitingNCT04615065

Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine

Acutelines: a Large Biobank Aiming to Improve Early Recognition of Acute Diseases, Contribute to the Development of Personalized Medicine and Optimize Short- and Long-term Outcome

Sponsor

University Medical Center Groningen

Enrollment

35,000 participants

Start Date

Sep 1, 2020

Study Type

OBSERVATIONAL

Conditions

Electrolyte disturbance Anaphylaxis Sepsis Dyspnea Thrombosis Pulmonary Embolism Pneumonia Acute Kidney Injury Frailty Emergencies Urinary Tract Infections Polypharmacy Skin Infection Syncope Shock Hemorrhage Acute Disease Complication of Treatment Intoxication by Drug

Summary

Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care. To overcome some of these challenges, the Center of Acute Care of the University Medical Center Groningen in the Netherlands, has established a de novo data-, image- and biobank named "Acutelines". Acutelines is initiated to improve recognition and treatment of acute diseases and obtain insight in the consequences of acute diseases, including factors predicting its outcome. Thereby, Acutelines contributes to development of personalized treatment and improves prediction of patient outcomes after an acute admission.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study, called Acutelines, is building a large collection of data and biological samples from patients who come to the emergency department with serious conditions. Researchers want to understand what happens in the body during life-threatening emergencies like sepsis, shock, kidney failure, and other urgent medical situations. By studying these patients, scientists hope to improve how we diagnose and treat serious emergencies in the future. The study collects information from medical records, imaging scans, and — for the most critically ill patients — blood and tissue samples. It is an observational study, meaning no extra treatments are given. Patients are simply asked if their existing medical data and samples can be used for research. You may be eligible if... - You are 18 years of age or older - You arrived at the emergency department with a high-priority triage status (red or orange) or arrived by ambulance/helicopter at yellow triage - You have one of the specific serious conditions listed: shock, suspected sepsis, acute kidney injury, anaphylaxis, syncope, intoxication, thrombosis, pulmonary embolism, bleeding on anticoagulants, GI bleeding, or electrolyte disturbance You may NOT be eligible if... - You were referred to the hospital for an organ transplant as a recipient - You were transferred from another hospital - Your contact with patient material was accidental (e.g., a work-related accident) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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