Early Phase 1 Function Clinical Trials
16 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–16 of 16 trials
Recruiting
Early Phase 1
Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.
post operative cognitive dysfunction
Minia University150 enrolled1 locationNCT06741566
Recruiting
Early Phase 1
Concomitant Renal and Urinary Bladder Allograft Transplantation
Chronic Kidney DiseasesBladder DysfunctionNeurogenic Bladder+6 more
Mayo Clinic30 enrolled2 locationsNCT04626167
Recruiting
Early Phase 1
Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Arterial HypertensionMicrovascular FunctionResistant Hypertension+1 more
National Institute of Cardiology, Laranjeiras, Brazil50 enrolled1 locationNCT06169241
Recruiting
Early Phase 1
Hydroxychloroquine in Children's Interstitial Lung Diseases With Genetic Causes
Interstitial Lung DiseaseSurfactant Dysfunction
Children's Hospital of Fudan University60 enrolled1 locationNCT04532346
Recruiting
Early Phase 1
Respiratory and Real-time Dynamics in Exercise-Induced Paradoxical Vocal Fold Motion
Vocal Cord DysfunctionExercise-Induced Vocal Cord DysfunctionParadoxical Vocal Fold Motion
Indiana University120 enrolled1 locationNCT07420530
Recruiting
Early Phase 1
The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response
Heat StrainHealthy Volunteer StudyKidney Dysfunction
Beth Israel Deaconess Medical Center28 enrolled2 locationsNCT06983730
Recruiting
Early Phase 1
Efficacy and Safety of Rifaximin-α in Treating MASLD
Metabolic Dysfunction-Associated Steatotic Liver Disease
Shanghai Changzheng Hospital60 enrolled1 locationNCT07381257
Recruiting
Early Phase 1
Intraoral Hypothermia Device for Preserving Taste During Radiation
Head and Neck CancerRadiation TherapyTaste Dysfunction
Henry Ford Health System15 enrolled1 locationNCT06579248
Recruiting
Early Phase 1
Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use
Endothelial DysfunctionInflammationElectronic Cigarette Use
University of Iowa24 enrolled2 locationsNCT06489249
Recruiting
Early Phase 1
Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM
Physical InactivityEndothelial DysfunctionGestational Diabetes
Anna Stanhewicz, PhD40 enrolled1 locationNCT06547619
Recruiting
Early Phase 1
Accelerated TMS for Seizure-Type Functional Neurologic Disorders
functional neurological symptom disorderFunctional Seizures
Medical University of South Carolina30 enrolled1 locationNCT07059325
Recruiting
Early Phase 1
Comparison of Antiplatelet Effects of Sotagliflozin to FDA-approved Antiplatelet Drugs
Platelet Function and Reactivity Tests
University of Michigan20 enrolled1 locationNCT06933056
Recruiting
Early Phase 1
Comparing Approaches to Assess Nitric Oxide-dependent Cutaneous Vasodilation
Endothelial function
University of Iowa56 enrolled1 locationNCT06499844
Recruiting
Early Phase 1
Prenatal Aspirin and Postpartum Vascular Function
PreeclampsiaMicrovascular Function
Anna Stanhewicz, PhD60 enrolled1 locationNCT05653973
Recruiting
Early Phase 1
Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes
Gestational DiabetesVascular Endothelial Function
Anna Stanhewicz, PhD28 enrolled1 locationNCT05946785
Recruiting
Early Phase 1
Role of NADPH Oxidase in Microvascular Dysfunction Following GDM
Gestational DiabetesOxidative StressVascular Endothelial Function
Anna Stanhewicz, PhD40 enrolled1 locationNCT05946798