Health-related Quality of Life Clinical Trials

22 recruitingLast updated: June 18, 2026

There are 22 actively recruiting health-related quality of life clinical trials across 19 countries. Studies span Not Applicable, Phase 4. Top locations include Boulder, Colorado, United States, Alofi, Niue, Basel, Canton of Basel-City, Switzerland. Updated daily from ClinicalTrials.gov.


Health-related Quality of Life Trials at a Glance

22 actively recruiting trials for health-related quality of life are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 11 trials, with the heaviest enrollment activity in Boulder, Alofi, and Basel. Lead sponsors running health-related quality of life studies include Longevity Metrics, Inc., Australasian Sarcoma Study Group (ASSG), and Aditi Bunker.

Browse health-related quality of life trials by phase

Treatments under study

About Health-related Quality of Life Clinical Trials

Looking for clinical trials for Health-related Quality of Life? There are currently 20 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Health-related Quality of Life trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Health-related Quality of Life clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Not Applicable

Mobile-Based Telemedicine and Health-Related Quality of Life Among Patients With Chronic Heart Failure (MOBILE-HF)

Health-related Quality of LifeChronic Heart Failure
Select College72 enrolled1 locationNCT07650474
Recruiting

Human Observatory Study

Musculoskeletal DiseaseDisability PhysicalNeoplasms+16 more
Longevity Metrics, Inc.1,000,000 enrolled1 locationNCT07646782
Recruiting

100-Year Human Aging Study

Disability PhysicalNeoplasmsCardiovascular Diseases+12 more
Longevity Metrics, Inc.1,000,000 enrolled1 locationNCT07563777
Recruiting
Not Applicable

Music Breathing in Enhancing Resilience Among Elders at Risk of Mental Health Problems

AnxietyDepressive SymptomLoneliness+2 more
Chinese University of Hong Kong40 enrolled1 locationNCT07631845
Recruiting
Not Applicable

CanSOLVE 2.0 Theme 3.1 Mind the Gap - Dialectical Behavioural Therapy (DBT) Skills Training Program Pilot

HemodialysisMental HealthHealth-related Quality of Life+2 more
University of Manitoba35 enrolled1 locationNCT07628309
Recruiting

Bile Acids Metabolism and Genetic Mutation Profile in the Intrahepatic Cholestasis of Pregnacy in Indian Population

Health-related Quality of LifeIntrahepatic Cholestasis of PregnancyGenetic Mutation
Post Graduate Institute of Medical Education and Research, Chandigarh150 enrolled1 locationNCT05691036
Recruiting
Phase 4

The Effect of Corticosteroids on Quality of Life Following Total Hip Arthroplasty: HIPSTER Study

Quality of LifeHealth-related Quality of LifePostoperative Quality of Recovery
Ziekenhuis Oost-Limburg224 enrolled2 locationsNCT07378215
Recruiting
Not Applicable

Decentralized Clinical Trial of Effectiveness of EnergyPoints App in Cancer Survivors

Fatigue in Cancer SurvivorsHealth-related Quality of LifeSleep Disturbances+1 more
5 Point App, Inc.180 enrolled1 locationNCT06754722
Recruiting
Not Applicable

Assessing the Effects of Cool Roofs on Indoor Environments and Health

Sleep QualityDepressionDehydration+22 more
Aditi Bunker3,200 enrolled5 locationsNCT06579950
Recruiting

Psychological Well-Being, Depression, and Health-Related Quality of Life in Adults With Type 2 Diabetes: A Cross-Sectional Study

Spiritual Well-beingDepressive SymptomsType 2 Diabetes Mellitus (T2DM)+2 more
National Taiwan University Hospital500 enrolled1 locationNCT07241325
Recruiting
Not Applicable

Cocreating Action to Improve Rationality in the Health System

Health-related Quality of LifeCommunity-Based Participatory ResearchHealth Literacy+7 more
Universidad Miguel Hernandez de Elche4,000 enrolled2 locationsNCT07237971
Recruiting
Not Applicable

Dyadic Sport Stacking Program for Mild Dementia and Their Family Caregivers

DementiaCognitionHealth-related Quality of Life+2 more
The University of Hong Kong144 enrolled1 locationNCT06597981
Recruiting
Not Applicable

Where Wild Things Grow: Nature- and Activity-based Group Interventions for Neurodivergent Children and Youth

AutismTourette SyndromeADHD - Attention Deficit Disorder With Hyperactivity+3 more
Sorlandet Hospital HF240 enrolled2 locationsNCT07203469
Recruiting
Not Applicable

Healthy Older Adults Through Movement and Engagement

FrailtyHealth-related Quality of LifeAgeing Well+1 more
Linkoeping University2,952 enrolled1 locationNCT07136168
Recruiting

Somatic Dysfunction in Patients With Acute Cerebrovascular Disease

Stroke, AcuteHealth-related Quality of LifeTIA+2 more
University of California, Davis120 enrolled1 locationNCT06605014
Recruiting

Translation and Validation of the French mPCOSQ (mPCOSQ-F).

Polycystic Ovary Syndrome Health-related Quality of Life
CHU de Reims350 enrolled1 locationNCT07016035
Recruiting

Effectiveness Evaluation of Social Prescribing

LonelinessHealth-related Quality of Life
Hvidovre University Hospital350 enrolled1 locationNCT07029334
Recruiting

The Impact of Supervision by a Health Care Professional on Quality of Life Questionnaire

Health-related Quality of Life
St. Claraspital AG200 enrolled1 locationNCT06490393
Recruiting
Not Applicable

A Community-based Program That Supports Physical Activity, Healthy Eating, Social Participation and System Navigation in Older Adults

Mobility LimitationHealth-related Quality of LifeHealthy Aging+1 more
McMaster University500 enrolled2 locationsNCT05008159
Recruiting
Not Applicable

Home-based Exercise and Physical Activity Intervention After Kidney Transplantation: Impact of Exercise Intensity

Exercise TrainingPhysical ActivityImplementation+6 more
KU Leuven147 enrolled2 locationsNCT06260579