Phase 2 HIES Clinical Trials
25 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 25 trials
Recruiting
Phase 2
Phase 2 Study of Rapcabtagene Autoleucel in Myositis
Idiopathic Inflammatory Myopathies
Novartis Pharmaceuticals123 enrolled58 locationsNCT06665256
Recruiting
Phase 2
Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients
Duchenne Muscular DystrophyDMDNeuromuscular Diseases+2 more
Satellos Bioscience, Inc.51 enrolled21 locationsNCT07287189
Recruiting
Phase 2
Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases
Behcet's DiseaseIdiopathic Inflammatory MyopathiesIgG4-related Disease
UMC Utrecht60 enrolled6 locationsNCT06285539
Recruiting
Phase 1Phase 2
Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot Study
Diabetic NeuropathiesDiabetic Peripheral Neuropathic Pain (DPN)
Florida A&M University20 enrolled1 locationNCT07298408
Recruiting
Phase 1Phase 2
Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT
LeukemiaInborn Errors of MetabolismHLH+11 more
Children's Hospital of Philadelphia100 enrolled1 locationNCT06839456
Recruiting
Phase 1Phase 2
Safety of Single and Repeat Dose of PYC-001 Eye Injections in People With Autosomal Dominant Optic Atrophy (Myrtle)
Autosomal Dominant Optic AtrophyOPA1 Gene MutationHereditary Optic Atrophies+1 more
PYC Therapeutics18 enrolled3 locationsNCT06970106
Recruiting
Phase 1Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Idiopathic Inflammatory MyopathiesSystemic SclerosisAntineutrophil Cytoplasmic Antibody-associated Vasculitis
Nkarta, Inc.144 enrolled15 locationsNCT06733935
Recruiting
Phase 2
Study of WAL0921 in Patients With Glomerular Kidney Diseases
Diabetic NephropathiesPrimary Focal Segmental GlomerulosclerosisMinimal Change Disease+2 more
Walden Biosciences96 enrolled50 locationsNCT06466135
Recruiting
Phase 1Phase 2
Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
HemoglobinopathiesMetabolic DisordersHematologic, Immune, or Bone Marrow Disorders+1 more
Washington University School of Medicine220 enrolled28 locationsNCT00920972
Recruiting
Phase 2
Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders
AMLMDSHLH+6 more
Memorial Sloan Kettering Cancer Center31 enrolled1 locationNCT04644016
Recruiting
Phase 2
Allo HSCT for High Risk Hemoglobinopathies
Sickle Cell DiseaseHemoglobinopathiesGraft Failure
Masonic Cancer Center, University of Minnesota62 enrolled1 locationNCT06872333
Recruiting
Phase 2
Formoterol in Diabetes
Diabetic Kidney DiseaseDiabetic Nephropathies
Medical University of South Carolina120 enrolled1 locationNCT07022418
Recruiting
Phase 2
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
Heart FailureCardiomyopathiesCardiogenic Shock+1 more
Stanford University50 enrolled5 locationsNCT06080074
Recruiting
Phase 1Phase 2
Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders
HemoglobinopathiesBone Marrow Failure SyndromesMetabolic Disorders+3 more
Washington University School of Medicine29 enrolled4 locationsNCT03128996
Recruiting
Phase 2
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
SclerodermaRheumatoid Arthritis (RA)Sjogren Syndrome+6 more
Artiva Biotherapeutics, Inc.90 enrolled26 locationsNCT06991114
Recruiting
Phase 1Phase 2
A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001
Retinal DegenerationRetinal DiseaseRetinal Dystrophies+2 more
PYC Therapeutics16 enrolled6 locationsNCT06852963
Recruiting
Phase 2Phase 3
Tailored Exercise Training Study Among Adults With HFpEF
Diabetic CardiomyopathiesHFpEF - Heart Failure With Preserved Ejection Fraction
University of Texas Southwestern Medical Center120 enrolled1 locationNCT07223242
Recruiting
Phase 1Phase 2
Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases
Sjogren SyndromeSystemic Lupus ErthematosusSystemic Sclerosis (SSc)+3 more
Peking University Third Hospital9 enrolled1 locationNCT06828042
Recruiting
Phase 2
Doxecitin and Doxribthymine in Adult Subjects With Thymidine Kinase 2 (TK2) Deficiency
MItochondrial MyopathiesThymidine Kinase 2 (TK2 ) Deficiency
Cristina Domínguez González15 enrolled1 locationNCT06754098
Recruiting
Phase 1Phase 2
Omega-3 Fatty Acid Lipidomics in Diabetes Peripheral Neuropathy
Diabetic Neuropathies
University of Iowa100 enrolled2 locationsNCT05169060