Phase 1 Hypertension Clinical Trials
36 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 36 trials
Recruiting
Phase 1
A Study on the Efficacy and Safety of Empagliflozin in the Treatment of Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
China National Center for Cardiovascular Diseases72 enrolled1 locationNCT06554301
Recruiting
Phase 1
Preliminary Human Trials of F230 Tablets
Pulmonary Hypertension
Beijing Continent Pharmaceutical Co, Ltd.136 enrolled1 locationNCT06899815
Recruiting
Phase 1
Study of KK3910 in Healthy Volunteers and Patients With Essential Hypertension
Healthy Volunteers Essential Hypertension
Kyowa Kirin Co., Ltd.160 enrolled3 locationsNCT06823947
Recruiting
Phase 1Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled29 locationsNCT06649110
Recruiting
Phase 1Phase 2
Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH.
Refractory Lupus NephritisSystemic SclerosisPrimary Sjogren's Syndrome Combined With Pulmonary Hypertension
Beijing GoBroad Hospital45 enrolled1 locationNCT06947473
Recruiting
Phase 1
Study of Intravenous ZMA001 in Healthy Subjects
Pulmonary Arterial Hypertension PAH
National Heart, Lung, and Blood Institute (NHLBI)96 enrolled1 locationNCT05967299
Recruiting
Phase 1Phase 2
CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH
Refractory Lupus NephritisSystemic SclerosisPrimary Sjogren's Syndrome Combined With Pulmonary Hypertension
Beijing GoBroad Hospital45 enrolled1 locationNCT06947460
Recruiting
Phase 1Phase 2
Sympathetic Mechanisms in Obesity-Crossover Design
ObesityHypertension
Vanderbilt University Medical Center12 enrolled1 locationNCT05312892
Recruiting
Phase 1
A Study of LY3971297 in Healthy Participants
ObesityHypertensionHealthy
Eli Lilly and Company225 enrolled7 locationsNCT06148272
Recruiting
Phase 1
Metabolic Imaging of the Heart Using Hyperpolarized (13C) Pyruvate Injection
HypertensionHypertrophy
Sunnybrook Health Sciences Centre112 enrolled2 locationsNCT02648009
Recruiting
Phase 1
A Study Evaluating the Safety and Tolerability of Artesunate in Patients With Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension PAH
Joseph C. Wu15 enrolled1 locationNCT06872112
Recruiting
Phase 1
Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults
Pulmonary Arterial Hypertension
Pharmosa Biopharm Inc.32 enrolled1 locationNCT06429930
Recruiting
Phase 1
Evaluate Efficacy, Safety, Tolerability and Biodegradation of PA5346 Ocular Implant in Patients With Open-Angle Glaucoma or Ocular Hypertension
Ocular Hypertension (OH)Open-angle Glaucoma (OAG)
PolyActiva Pty Ltd12 enrolled3 locationsNCT06964061
Recruiting
Phase 1
Safety and Pharmacokinetics Study of BCD101 in Healthy Volunteers
Essential Hypertension
Bichedam Co., Ltd.56 enrolled1 locationNCT07282145
Recruiting
Phase 1
The Effect of an Oral Nutritional Supplement on the Nutritional and Health Outcomes of the Elderly
Body WeightHypertensionIron-deficiency+4 more
University of Ghana80 enrolled1 locationNCT06773975
Recruiting
Phase 1Phase 2
AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension
Open Angle GlaucomaOcular Hypertension
AbbVie96 enrolled49 locationsNCT04499248
Recruiting
Phase 1
VB19055 Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in a Healthy Chinese Population
Hypertension
Zhejiang Yangli Pharmaceutical Technology Co., Ltd.86 enrolled2 locationsNCT07254481
Recruiting
Phase 1
A Placebo-controlled, Randomized Clinical Trial to Assess the Safety, Feasibility, and Pharmacokinetics of Microbiota Transplant Therapy With Antibiotic Preconditioning and Fiber Supplementation in Patients With Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
University of Minnesota24 enrolled1 locationNCT06481852
Recruiting
Phase 1
: Vascular Function in Health and Disease
Heart FailureHypertensionChronic Obstructive Pulmonary Disease+1 more
Russell Richardson420 enrolled1 locationNCT02966665
Recruiting
Phase 1
To Evaluate the Efficacy and Safety of KN060 in Essential Hypertension
Hypertension
Suzhou Alphamab Co., Ltd.60 enrolled1 locationNCT07191899