Phase 2 Hypertension Clinical Trials
76 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 76 trials
Recruiting
Phase 2
A Phase II Clinical Trial of Efficacy and Safety of SAL0140 at Different Doses in Patients With Uncontrolled Hypertension
Uncontrolled Hypertension
Shenzhen Salubris Pharmaceuticals Co., Ltd.252 enrolled1 locationNCT07654140
Recruiting
Phase 2
A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran
Hypertension
Alnylam Pharmaceuticals93 enrolled3 locationsNCT07553442
Recruiting
Phase 2
Spironolactone for Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
National Institutes of Health Clinical Center (CC)70 enrolled1 locationNCT01712620
Recruiting
Phase 2
Using Mobile Stress Management to Reduce Hypertension in African American Men
Hypertension
ISA Associates, Inc.135 enrolled1 locationNCT07594808
Recruiting
Phase 2
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
Hypertension (HTN)
Novartis Pharmaceuticals323 enrolled7 locationsNCT07543120
Recruiting
Phase 2
A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
Pulmonary Arterial Hypertension PAHPulmonary Hypertension, Interstitial Lung Disease
AllRock Bio, Inc.40 enrolled19 locationsNCT07175038
Recruiting
Phase 2
Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
Pulmonary Arterial Hypertension PAH
Regeneron Pharmaceuticals99 enrolled6 locationsNCT07318597
Recruiting
Phase 2
Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)
Hypertension, Pulmonary
Merck Sharp & Dohme LLC130 enrolled57 locationsNCT06814145
Recruiting
Phase 2
A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489
Pulmonary Hypertension
Pfizer36 enrolled48 locationsNCT07073820
Recruiting
Phase 2
A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.
Chronic Kidney Disease and Hypertension
AstraZeneca218 enrolled71 locationsNCT07222917
Recruiting
Phase 1Phase 2
A Phase Ⅰb/Ⅱa Clinical Study of IMC-003 Injection for the Treatment of Pulmonary Arterial Hypertension Receiving Background Therapy.
Pulmonary Arterial Hypertension PAH
ImmuneCare Biopharmaceuticals (Shanghai) Co., Ltd.120 enrolled32 locationsNCT07593027
Recruiting
Phase 2
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
Chronic Obstructive Pulmonary DiseaseDyspneaPulmonary Hypertension
VA Office of Research and Development126 enrolled5 locationsNCT05937854
Recruiting
Phase 2
A Trial of "APL-9796'' in Adults With Pulmonary Hypertension
Pulmonary Arterial Hypertension
Apollo Therapeutics Ltd48 enrolled6 locationsNCT06846554
Recruiting
Phase 2
Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia
Hypertension
Massachusetts General Hospital90 enrolled2 locationsNCT07238400
Recruiting
Phase 2
Study of Efficacy and Safety of Tonlamarsen in Participants With Acute Severe Hypertension Recently Discharged From the Hospital
HypertensionAcute Severe Hypertension
Kardigan, Inc.100 enrolled4 locationsNCT07511361
Recruiting
Phase 2
Repurposing Valsartan May Protect Against Pulmonary Hypertension
Pulmonary Arterial HypertensionRight Ventricular DysfunctionRight Heart Failure+1 more
University of Washington60 enrolled1 locationNCT06053580
Recruiting
Phase 2
A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients
Hypertension
Novartis Pharmaceuticals380 enrolled84 locationsNCT06857955
Recruiting
Phase 1Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled85 locationsNCT06649110
Recruiting
Phase 2
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
Uncontrolled Hypertension
Retension Pharmaceuticals. Inc.280 enrolled20 locationsNCT07142356
Recruiting
Phase 2
A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
Cardiovascular DiseasesFibrosisLung Diseases+3 more
Pulmovant, Inc.20 enrolled1 locationNCT07333183