Phase 4 Hypertension Clinical Trials

74 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 74 trials

Recruiting
Phase 4

Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular Hypertension

GlaucomaOcular Hypertension
Indiana University50 enrolled1 locationNCT07588152
Recruiting
Phase 4

Treatment With Aspirin After Preeclampsia: TAP Trial

Cardiovascular DiseasesHypertensionPregnancy Complications+8 more
Malamo Countouris60 enrolled1 locationNCT06281665
Recruiting
Phase 4

PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and Efficacy

Postpartum Hypertension (PPHT)
University of California, Los Angeles110 enrolled1 locationNCT06915792
Recruiting
Phase 4

Pulmonary Hypertension: Intensification and Personalisation of Combination Rx

Pulmonary Arterial Hypertension
Sheffield Teaching Hospitals NHS Foundation Trust40 enrolled1 locationNCT05825417
Recruiting
Phase 4

Sotatercept in Pulmonary Arterial Hypertension

Pulmonary Artery Hypertension
University of Alberta27 enrolled1 locationNCT07140484
Recruiting
Phase 4

Effect of the Traditional Chinese Medicine Yufeng Ningxin in Patients With Hypertension

HypertensionEssential (Primary) Hypertension
Beijing Anzhen Hospital350 enrolled16 locationsNCT07607275
Recruiting
Phase 4

Pre-discharge Influenza Vaccination in Patients Hospitalized for Acute Cardiac Conditions

Myocardial InfarctionAcute Heart Failure (AHF)Arrhythmias+3 more
Wroclaw Medical University400 enrolled1 locationNCT07617376
Recruiting
Phase 4

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

PreeclampsiaHypertensive Disorders of PregnancyGestational Hypertension
Ohio State University10,742 enrolled16 locationsNCT06468202
Recruiting
Phase 4

24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients

Open Angle GlaucomaOcular Hypertension
Mayo Clinic30 enrolled1 locationNCT07325240
Recruiting
Phase 4

Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis

CirrhosisAscitesPortal Vein Thrombosis+3 more
Asian Institute Of Medical Sciences220 enrolled1 locationNCT07521332
Recruiting
Phase 4

Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

HypertensionLeft Ventricular Hypertrophy
Brigham and Women's Hospital75 enrolled1 locationNCT05593055
Recruiting
Phase 4

Clinical Trial to Evaluate the Efficacy and Safety in Concomitant Administration of Macitentan and Dapagliflozin in Patients With Heart Failure With Mildly Reduced and Preserved Ejection Fraction (HFmrEF and HFpEF) and Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH)

Group 2 Pulmonary HypertensionHFpEFHFmrEF+2 more
Gachon University Gil Medical Center64 enrolled15 locationsNCT07147114
Recruiting
Phase 4

Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension

Tourniquet HypertensionIntraoperative HypertensionTotal Ankle Arthroplasty+1 more
Duke University40 enrolled1 locationNCT04454203
Recruiting
Phase 4

Antihypertensive Mechanisms of Minocycline in Resistant Hypertension

Hypertension Resistant to Conventional Therapy
University of Florida120 enrolled1 locationNCT06246396
Recruiting
Phase 4

Effects of SGLT2 Inhibitors in Pre-heart Failure Populations With Hypertension

HypertensionPre-Heart Failure
China National Center for Cardiovascular Diseases120 enrolled2 locationsNCT06055452
Recruiting
Phase 4

Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

Open Angle GlaucomaGlaucomaOcular Hypertension+1 more
University of Miami20 enrolled1 locationNCT07217678
Recruiting
Phase 4

A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)

Cardiovascular ComplicationPre-EclampsiaGestational Hypertension+2 more
University of Michigan200 enrolled1 locationNCT06785116
Recruiting
Phase 4

Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)

Hypotension and ShockPulmonary Hypertension of the Newborn (PPHN)Hypoxemic Respiratory Failure
University of California, Davis30 enrolled1 locationNCT07322133
Recruiting
Phase 4

The Impact of IV Iron on Exercise Capacity and Quality of Life in Pulmonary Hypertension

Pulmonary HypertensionIron-deficiency
Ziekenhuis Oost-Limburg306 enrolled7 locationsNCT07359599
Recruiting
Phase 4

Impact GLP-1 Agonists Following Bariatric

Diabetes MellitusMetabolic SyndromeHypertension+2 more
University of Missouri-Columbia150 enrolled1 locationNCT06132477